Elevated liver function tests led to a diagnosis of PBC in October 2016. (Positive AMA and liver biopsy, moderate to severe cirrhosis stage 4). Is my thinking correct that PBC caused the cirrhosis but that PBC is no longer really the issue? The end stage of both diseases is the same (ascites, varices, brain fog, itching, etc). Additionally, if cirrhosis is irreversible (stage 4 scarring), why would weight loss help. In my mind, what’s done is done. Other than fatigue and occasional itching, I am asymptotic.