News on PBC clinical trial progress

[EileenUSA]

Hello friends,

I have been following this companies exciting research as they have been developing a nano-particle platform geared at addressing the dysregulated immune system/Autoimmune disease PBC, Celiac Disease, Mystanstia Gravis etc..

Here's quote from latest news as they just received orphan drug designation for CNP-104.

"The FDA has granted Cour Pharmaceuticals orphan drug designation for CNP-104, a biodegradable nanoparticle in development for the treatment of primary biliary cholangitis, the company announced in a press release.

According to Cour, CNP-104 initiates tolerance to pathogenic activated pyruvate dehydrogenase complex-E2 T-cells that “drive inflammation in bile ducts, leading to improvement in clinical outcomes of liver health.”

healio.com/news/gastroenter...

[4pjx__]

Hi Eileen,

I have been participating in this trial. They gave me a couple of infusions and are following me for 2 years. It will be 2 years in March. Not sure if I got the placebo. I haven’t seen any improvement in my labs but we do know that I didn’t get any worse. These are really encouraging results though. Thanks for posting

-Pam

[DonnaBoll Administrator]

I did hear on The PBC Foundation's Q&A today that there were several new drugs on the horizon this year. Researchers are working tirelessly to help so many who suffer from auto immune diseases. Keep up posted on the trial.

[Juhainar]

oh that is great! Thank you for sharing.

I was wondering if any of anyone here is volunteering for PBC research with a hospital or university that’s working to uncover the cause of this disease

[ninjagirlwebb]

thank you for sharing