I was diagnosed in 2016 and have been on URSO since then. Thought to have been in very early stages. Labs initially only slightly elevated (Alk phos and ALT) but quickly normalized. MRE (MRI with Elastography -thought to be more sensitive than fibroscan) 3/2016 showed no fibrosis only inflammation - stage 0-1.
In past month slight elevation of ALT-36 ( 20-32) and decrease in total protein 5.9 ( 6-8.5), all other labs normal. Had repeat MRI which shows overall fibrosis stage1-2 and focal areas stage 2-3
Am I considered a non responder now?? My hepatologist told me he thought it was unlikely I was ever going to progress. Very concerned about this degree of progression in 18 months. My understanding is this is a poor prognostic sign.
Should I ask about Oclavia?