urso medication: mg/kg and when is the best time to take them

[Andrei]

hello!I was wanderind about the correct therapy with urso!

I read that the dose must be 13 mg per kg.If it is more is not ok because the side efects will appear.

if is less than 13,5 mg per kg whe treatment is not enought to slow down the progresion.

all that i wroted above is taken from more than 3 trial studies.

another thing that i saw that is in discution is that the urso is recomended to be taken diffrent.

Some dr s recomend that the dose to be taken in fragments and others recomend that urso should be taken in one dose per day.

So i think that we all should see if we take it correct.

For example I am 80 kg and my dose is 1000 mg per day .I take it all (4pcsx250mg) before i go to sleep.

i also take lagosa (silimarine) 2/day (morning/evning)

i thing we can share our methods of taking the treatmend and so we can have a general ideea about it.

best regards to all of u!

[donna01]

I take 1 pill 3 times a day. It is 300 mgs.

[Andrei in reply to donna01]

how many kg?

[donna01 in reply to Andrei]

I' m not sure what you're asking.. I live in the U.S. Are you referring to my weight?

[Andrei in reply to donna01]

yes.The optimal dose should be 13.5 mg x your weight (kg)

[donna01 in reply to Andrei]

I don't know my weight in kgs.. I only know pounds (lbs). I weigh 138 lbs.

[Ballymahon2]

Where do you live andrei

[Andrei in reply to Ballymahon2]

romania

[Ballymahon2 in reply to Andrei]

Lovely country

[Andrei in reply to Ballymahon2]

pitty that is populated

[Ballymahon2 in reply to Andrei]

I have been to bucharest and transylvania very nice

[Catherine3883]

I weigh 59kg, I take 3 in the morning- 750mg and 500mg at night. It was recently upped as my levels were going up. I was told to take it twice a day with/after food to stop gastric irritation

[Guardiangecko]

I was Dx 3/26/18. Due to family history of PBC, my Liver specialist said he was going to max dose me. I weigh about 83 kg. I take 2 cap x 300mg twice daily (1200 mg/daiiy). I take it at 7:00 am and 7:00 pm.

[Hidden]

I was diagnosed 8 years ago, and weighed 68kg and and over time I gained weight and went up to 77kg at this weight I was taking 1000mg a day in two doses, but that was only 12mg per kg of body weight that’s when I decided it was time to diet and loose some weight during this time I was on the same dose of urso.

After loosing the extra weight I now weigh 66kg and I’am happy with that weight and I still take 500mg in the morning and 500mg in the evening , both with a meal or I get stomach issues.

So I’am now taking 15mg per kg of body weight which is the upper limit.( I read the dosage was 13/15mg per kg of body weight).

Just recently seen my consultant who immediately picked up on the weight loss and congratulated me on loosing it. She said to stay on the same dose as all my numbers were stable and the Alp had in fact come down a little in the last year and to continue taking it twice a day. With my morning dose I also take my vitaminD tablet.

[Andrei]

i understand that some dr s recomend that a part of the dosage should be taken at 12 a clock in the morning because in the morning the liver is working better and after the first part of the day it slows down.

the other part of the dosage should be taken in the evening

[Wocket]

I am 80kg and take 2 x 250mg at breakfast and lunch. Can’t take it in the evening as I get terrible acid when I go to bed.

[Margaret59]

I take the amount as yourself, I take 2 with breakfast & 2 with my evening meal as directed by my consultant. I also take other medicines for various problems to.

[nonnatwoxtwo]

I take mine in the morning and early afternoon with food. Can't take in the evening as the medication gives me terrifying nightmares.

[Lezley23]

I take all my tablets together in the morning If I remember. And quite often i forget to take them, So I take them when I remember. My memory is getting quite bad.

[enalynot]

I take 1000mg a day I take mine with my evening meal if I take on their own it tastes awful when it repeats

[enalynot]

Forgot to mention that my consultant thought the urso was in liquid form so was told to take all at once to get it over with with my evening meal

[58goose]

I weigh about about 77kg and take 1000mg a day - 2 X 500mg with my evening meal. It was recommended that I took them later in the day as I have to take other meds earlier in the day. If I take them without food they cause nausea.