Sorry for so many questions but I have been flying solo for 5yrs and I am my doctor's only patient. I have read here that some PBC patients have flare ups. Could you describe symptoms that let you know that you are having a flare up? I pretty much have no symptoms other than wanting to sleep all the time. I get random elevations with my ALP jumping 100 points at a time, which are only captured by routine LFTs. I thought if I knew more about what to look for I could be more proactive some how. Also I probably should ask if there is anything to be done regarding a PBC flare.