After having elevated enzymes for at least a year and a half, I saw a liver specialist on July 6th. I was leaving for a three week vacation in Hawaii the next day. They did blood work and scheduled an MRI and liver biopsy for the day after I got back. The nurse notified me the next week that the blood work identified my diagnosis with PBC and the doctor wanted me to start on 1000 mg of Ursodiol asap, so they sent a prescription to a pharmacy in Hawaii. They cancelled the MRI, but still wanted the liver biopsy. Read all about PBC and it really was kind do scary! With having jet lag and then the biopsy, I was washed out for the first week. I seem to be having some days of fatigue now. I did not have any symptoms besides the enzymes. It has helped to read the posts from all of you that have PBC.