I'm really a bit worried now my hands shake quite a bit and my joints are painful especially my right shoulder. I've read on here that shoulder pain is common but what about the shakes? It's not all the time but at times it's quite noticeable by others. My partner says that I've changed over the past months, even before PBC was diagnosed. Thinking about it he's right. I feel anxious, tired and I know that I'm suffocating him at times. What's going on? I am a very intelligent person currently off work due to fatigue and never had thoughts that he would get up and leave me. Me don't live together but we are very close and have been together for a numbe of years. Is it possible the PBC is responsible or am I just going through a crazy stage? He says I blame PB C for everything and when we go for my blood results on Wednesday he will ask if memory loss is a symptom. last time I saw the doctor at St James hospital and said I had pain under my ribs and believed it was liver pain he said "nothing to do with PBC". Later I read that this is a symptom. I'm afraid I don't have a lot of faith in what's going to be said me next week and I just hope the Urso is working and my craziness is down to not knowing if the meds are working. This sounds crazy but that's exactly how I feel.