Cyancobalamin versus hydroxocobalamin

[Io1000]

I have accidentally purchased ampoules of cyanobalamin instead of hydroxybalamin.Am I able to use this instead as at the moment can’t find a site with hydroxy. Available.

[wedgewood]

You can use the Cynocobalamin ampoules without any worry , as long as you do not have an eye condition known as. Leber’s . Cynocobalamin is widely used in USA . You might need to inject more often that with Hydroxocobalamin. I am using Pascoe B12 depot whilst Panpharma is out of stock ( for the umpteenth time )

Here is some information that might be useful

The following reliable German online Pharmacies (all registered with the German Health Authorities ) will deliver VitaminB12 Depot ( Hydroxocobalamin)single use ampoules to the U.K.

vesandapo.de( in Leipzig) Site is in German . Use Google Chrome for translation . This is usually the best value pharmacy. U.K. is “Vereinigtes Königreich”

Courier cost €9.99

apohealth.de ( in Munich) Site available in English . (Union flag , bottom left on my device .)

Courier cost €20.00 for 10 packets . Lower cost for fewer packets .

apotheke-marienbrunn.de( in Leipzig) Use Google Chrome for translation . Also deliver to Australia , New Zealand and USA . Drop-down country list is in German and U.K. is called

“Vereinigtes Königreich Großbritannien und Nordirl”

juvalis.de Use Google Chrome for translation

fixmedika.de obtainable in English ( but delivery costs €45.00 !!!!!!)

First of all register with the pharmacy .

When filling out the address form, you will see that the country is already filled out with Deutschland / Germany .You must first change that to your own country by using the drop-down list to — U.K., United Kingdom , Vereinigtes Königreich, Grossbrittanien . — however it is expressed.Do this so that your post-code and the rest of your address is accepted . Otherwise,you will be unable to order , and you will be tearing your hair out

amazon.de also sell Pascoe and Hevert . But depending on the supplying pharmacy, may or may not supply to the U.K. You can’t use the Pharmaceutical reference numbers to order from amazon.de . You must use the brand names .

The following brands are usually available.

PANPHARMA ( formerly Rotexmedica)

1mg x 1 ml ampoules b12 DEPOT ( Hydrocobalamin)

Packet of 10

Pharmaceutical reference number 16199653

Most popular ampoule . Good value , but often out of stock .

PASCOE b12 DEPOT packet of 10 —1.5mg x 1ml ampoules

Reference no. 07568672

Packets of 10 x 10 ( 100 ampoules ) Reference no.07568695

The Pascoe are much cheaper per packet if you buy the offer of 10 packets . If you inject weekly or more frequently, you will be covered . Otherwise , some ampoules may become out of date .

HEVERT B12 DEPOT 1mg x 2ml ampoules 1 packet of 10 reference no. 06078368

HEVERT B12 DEPOT 1mg x 2ml 10 packets (100 ampoules ) Reference no. 06078380

Use the Pharmaceutical Reference numbers to order from the pharmacies, it’s easier , but not if buying from amazon.de

The above brands also produce Cynocobalamin B12 single use ampoules. They are cheaper than Hydroxocobalamin., but reputed not to stay in the system as long. Fine to use as long as the patient does not suffer from the rare eye-condition called LEBERS. Cynocobalamin is widely used in the USA I do not have the Pharmaceutical reference numbers for the Cynocobalamin ampoules.. Cynocobalamin is referred to as vitamin B12. Hydroxocobalamin is referred to as vitamin B12 depot.

PLEASE BE AWARE OF THE FOLLOWING .

Now that the U.K. has left the EU , there is a limit to the value of goods that we can order before tax is due .Tax is applicable if the value exceeds £135.00 ( roughly €158.00 at todays rates — look it up to make sure ) Value does include delivery cost ! On top of that , Royal Mail charges £8.00 for handling.

I’m not sure how much the tax is , so please look it up .A member was quite shocked at what she had to pay when she exceeded the limit . YOU HAVE BEEN WARNED!

With best wishes .

[Io1000 in reply to wedgewood]

Thank you so much wedgewood.I was in a bit of a panic.I have used some of the cyano and it doesn’t last as long.Your reply explains it…I thought it was me being stupid.I will try to get some hydroxy.via the various routes you suggest.Thank you for such a comprehensive reply.Best wishes Ann

[Nackapan in reply to wedgewood]

Versanapo order for hydrox panpharma 1mg/ 1mlSo far going through 🤞

[helvella]

You might find this of some interest (and, probably, reassurance):

helvella - Cyanide Content of Cyanocobalamin

A discussion about the cyanide content of cyanocobalamin based on fundamental chemical composition.

helvella.blogspot.com/p/hel...

If anyone finds anything wrong or misleading there, please let me know.

[Io1000 in reply to helvella]

Thank you Helvella.

[clivealive Forum Support]

I'm in the UK and have a NHS prescription for cyano (which I have been on for 52 years) still "unfilled" after six weeks.

I have only two vials left both of which will have "expired" at the end of April (tomorrow).

[Io1000 in reply to clivealive]

Hello Clive,Does this mean you are going to be short of B12 and unable to get on prescription.I hope this isn’t so and I haven’t understood correctly.

I won’t waste my cyano as it’s in date until next year.Best wishes Ann

[clivealive Forum Support in reply to Io1000]

Thank you - I'll keep my fingers crossed - but that does make typing difficult 😃😃

May I ask where you sourced the cyano from?

I was diagnosed with P.A. back in 1972 and prescribed the cyano every four weeks for the rest of my life - either that or eat raw liver three times a day.

I guess the injections must be working as I'm coming up to 83 in June.

I wish you well.

[Io1000 in reply to clivealive]

hello again Clive,I got the cyano from Amazon.de but that was some time ago.Well done on reaching 83.its not an easy battle I know but it’s worth it.I am 87 this year! The best of wishes to you.Ann

[Nackapan in reply to clivealive]

Hopefully your prescription will be done soon.Ate they waiting for more stock then ?

[wedgewood in reply to clivealive]

You can obtain Cynocobalamin ampoules from amazon.de. ( obtainable in English ) Made by Pascoe and called B12 injectopaz They are 1mg x 1 ml . They also make Hydroxocobalamin which is called B12 depot . So don’t get confused ! if you decide to get some . Best wishes .

[clivealive Forum Support in reply to wedgewood]

Thanks wedgewood I'll try to remember that.

Supplies of cyano in the UK always seem to become "sricky" when the expiry date comes round.

Take care now.

[WIZARD6787]

I did trials of both cyanocobalamin and hydrocobalamin. Keeping frequency and amount the same and found them to be equivalent at that time.

[Io1000 in reply to WIZARD6787]

Thank you wizard,that’s reassuring.

[am111]

Cyano is absorbed much less by the body than hydoxy, so you need either a higher dose or more frequent injections. The former idea doesn't often work very well, as the absorbed amount of cyano increases very little after a certain point, so more frequent injections is what you have to do...

[Rubyroo10]

I did that too and due to cost are using them and I am OK

[Rubyroo10]

I inject more frequently too than with the hydroxocobalamin

[ReallyWondering]

I'm in the US, so they only prescribe cyanocobalamin. I've been injecting it weekly for six months and it works fine for me. All symptoms subsided, with the exception of some minor vibrations in my feet.

[Io1000 in reply to ReallyWondering]

Interesting to know the differences in our two countries and comforting to know it works for you.

[MoKayD]

Cyanocobalamin works great for me. I been on it for years now.

[Io1000]

thank you MoKayD.Are you in the U.K. ?