Do expired B12 hydroxocobalamin ampoules still work?

[jkiron]

Do expired B12 hydroxocobalamin ampoules still work? I still have at least forty that expired back in February. I feel like they may not be working as I've had to increase SI from every other week to every week to feel normal again.

[wedgewood]

I would say that their potency is being gradually reduced . But I believe that they are harmless .

[wedgewood in reply to wedgewood]

They will be harmless , but you don’t want harmless , you want effectiveness !

[jkiron in reply to wedgewood]

Thank you all for your tips.I feel pretty stupid bringing back all old symptoms by using the old ones. I’ve just ordered a box of 100 from versandapo. Going forward I’ll store them in the cellar and dispose on expiry date. Thank you all for your community support!

[Nackapan]

I think you've answered your own question. I personally wouldn't use them unless desperate .

Horrible to inject with uncertainty

[Baggy8]

I’ve used them for that extra couple of months, then their effectiveness falls off a cliff.

[am111]

B12 can disintegrate from heat and light. If you store in the fridge (not freezer) at around 2-8 degrees, it will last a long time. If only at room temperature, it will disintegrate over time.

[helvella in reply to am111]

Auto-defrost refrigerators can be a problem. Both when they warm during defrost and when they cut in and restore coolth (which can result in freezing especially of smaller items).

[tomdickharry]

Until a couple of months ago I was using date-expired ampoules but they were not very effective at all. I supplemented with huge doses methylcobalamin swallowed until I managed to get 1500µg capsules from Amazon.de.

Best ever.

[PaintLadie]

I am using hydroxocobalamin with an expiry of 1/2023. I am not going to let it go to waste. It works fine although I am inj. more than 1ml daily just incase it has lost some potency. My symptoms usually come back immediately even after skipping one dose. So I would most definitely notice if it did not work and so far it is still working.