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Everything you always wanted to know about vit B12 metabolism but were afraid to ask

jade_s profile image
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Ran across this paper from 2022. Gives an impressive but understandable overview of B12 metabolism from ingestion to cellular uptake, including a straightforward overview of the required transporters and associated genes. Pitfalls of various b12 related blood tests are discussed. PA & folate issues are briefly addressed. Includes some fun diagrams. Overall looks like a comprehensive and good overview of B12D! Bonus, it's open access so freely available for all to read.

mdpi.com/2218-1989/12/11/1104

Kósa, Magdolna, et al. "Vitamin B12 (Cobalamin): Its Fate from Ingestion to Metabolism with Particular Emphasis on Diagnostic Approaches of Acquired Neonatal/Infantile Deficiency Detected by Newborn Screening." Metabolites 12.11 (2022): 1104.

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MrsTuft profile image
MrsTuft

It makes me wonder what effect my B12D has had on my daughter…

Rexz profile image
Rexz

Thank you jade_s! That is a very well written easily understandable paper.

Rexz

Wwwdot profile image
Wwwdot

Hi jade

Great find and thank you for sharing.

🤗🤗

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