Uric acid

[Mozza127]

Just wondering if any one has any developments due to b12 or lack of B12 with uric acid levels relating in goutCheers

[Gambit62 Administrator]

B12 is known to increase the chances of gout - folic acid decreases it. As people who are B12 deficient are often folate deficient it's more likely to be the folate deficiency causing the gout.

[Mozza127 in reply to Gambit62]

Thankyou very interestingNot sure how folate works

[Technoid in reply to Mozza127]

On Folate, from Mayo Clinic:

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"Folate (vitamin B-9) is important in red blood cell formation and for healthy cell growth and function. The nutrient is crucial during early pregnancy to reduce the risk of birth defects of the brain and spine.

Folate is found mainly in dark green leafy vegetables, beans, peas and nuts. "

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On risks/exacerbating factors for Gout, from the CDC:

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Being male

Being obese

Having certain health conditions, including:

* Congestive heart failure

* Hypertension (high blood pressure)

* Insulin resistance

* Metabolic syndrome

* Diabetes

* Poor kidney function

Using certain medications, such as diuretics (water pills).

Drinking alcohol. The risk of gout is greater as alcohol intake goes up.

Eating or drinking food and drinks high in fructose (a type of sugar).

Having a diet high in purines, which the body breaks down into uric acid. Purine-rich foods include red meat, organ meat, and some kinds of seafood, such as anchovies, sardines, mussels, scallops, trout, and tuna."

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[helvella in reply to Technoid]

I find the Office of Dietary Supplements papers quite helpful. More comprehensive than many other sources.

Folate

Fact Sheet for Health Professionals

ods.od.nih.gov/factsheets/F...

Screenshot of part of ODS folate sources table.