Does anyone know anything about methylated vitamins - I feel worse when I take them, but I’m confused about this as I’ve MTHFR mutations and it’s meant to help! I also worry B6 is part of my neuro issues. My levels stay very high even without supplementing - I have a very good diet (or maybe I can’t absorb it so it just floats around my body?). I’d like a multivitamin, without methylated vits, and low or no B6, but such a thing doesn’t seem to exist! I’m coeliac and tendency towards nutrient deficiencies and have always been told to take a multivit, plus B12 is meant to work best when you add b complex, but can’t find one I can tolerate. I’m 12 months into ED SI Hydroxo - I’m loads better than I was but still gave significant fatigue and some leg weakness / numbness / pain. Thoughts?
Question about methylated vits and Vi... - Pernicious Anaemi...
Question about methylated vits and Vit B6.
You've probably seen this one (linked below) without B6 - it does have methylfolate and methylcobalamin but the amounts are very small. The B12 amount, 50mcg is barely over the lowest minimum maintenance dose sometimes mentioned for B12 supplementation for vegans, I know you're not taking it for the B12 but its such a low dose that I wouldnt even rely on it myself for maintenance B12 dosage, thats how small it is. The folate is 8 times less than the 400mcg often recommended for supplementation for women of childbearing age.
The one suggested has no b6.I've used many brands . All have tiny amounts of b6 lamberts 4mg.
I ve tried b6 short term at 50-100 to see if fatigue improved and balancing hormones.
Noticed no particular difference.
I have an ongoing vestibular disorder.
Also I'm very sensitive to alot of things.
The only way to tell is stopping stuff and recording .
I took a while to even tolerate vitamin D .
Had to take it though as level was down to 21 . Was not taking anything else at the time not even on b12 as first thing to plummet.
So know for sure it was the vit D .
Hope you find a way.
Or just stop for a week. ??
I think I replied to you that its methylated? The reply about B6 was to another kind responder. I can find unmethylated with B6 and methylated without! 😩. The search continues… More than 10mg B6 can cause neurological issues so I’m glad you stopped that. There are so many underlying causes of vestibular issues. Mine is vestibular migraine. I hope we get sorted!!!
What a misery vestibular migraine must be for you to have to endure. I wondered if you had seen the link attached which might be of interest. The latter is something I have recently purchased to try.
seekinghealth.com/blogs/edu...
Individuals who have issues with Methylation, may require pre-methylated forms (methyl, or more active forms) of some of these vitamins to utilise due to their Methylation issues. A few of these include: Vitamin B6 – Active form: Pyridoxine-5-phosphate (P-5-P)
My VM was under control until I had major surgery which tanked my B12 and triggered my VM again. My neuro is giving me nerve blocks to stop them. It's slowly improving. I need to avoid methylated vits - Seeking Health from your link are great but their products contain B6 which I'm already too high in. I may have to use single supplements....
I hope your surgery went well allbeit you have paid heavily for it. 😩 It's a case of two steps forward and god knows how many back. I hope the nerve blockers are helping you.
It sure robs your pocket when having to buy supplements single......as well I know. Somebody put a video on here of how to repair nerve damage and in for a penny in for a pound I purchased all the supplements. I hope you find something to help you. 💐
Thank you it was successful but devastating! Yes I am steadily improving. Thank you. What’s the link to the video please? X
This is the video of supplements that I have purchased to see if they help. youtube.com/watch?v=opvpUdX...
I brought the L-Cartine in a liquid capsule from here myprotein.com/nutrition/vit...
It is to soon to say if any of these supplements are helping.
Anything is worth a try. 😘
Have you noticed any improvements since supplementing? Early days no doubt...interesting links, thank you!
It was a video put on by someone else.
I brought the supplements but if honest didn't take them long enough because together with my other meds it was rather a lot to take.
I think we are all looking for a miracle cure for the misery of neuropathy. If only they did one pill instead of having to take so many I would have continued.
I'm still suffering. 😩
Yes I get those too.Used to be awful .
Always in sone sort of event that differed in severity .
The longest one wax 6 days of hell
It's all improving over time .
Far less severe and much less often.
B6 made no difference to me .
At one point thought a little more energy and even mood.
I trial things with copius notes over the last 4 years.
What helped greatly was vestibular physiotherapy.
And looking at diet
Pysio
Got me walking initially.
Then had to stop as triggered migraines.
Then managed last year another course at a steady pace and try and incorporate exercises into everyday things.
Worth looking into.
'Cawthorne ' exercises.
The vitamer of B6 appears critical. Have a look here:
Why don't you use a basic supermarket A-Z multivitamin and mineral supplement?On the whole they are much better than any fancy branded ones - because they have to conform to more broadly accepted regulations, have more testing (both manufacturing AND by the seller), and don't use methylated vitamins.
Lots of people, including me, buy into the concept of "you get what you pay for", so tend to assume more expensive is better, but it isn't always the case!
In the generic A-Z ones, B12 is usually cyanocobalamin, folate is folic acid and B6 is low.
I'm intrigued... What caused you to get your B6 tested? Was it just done as part of a vitamin and mineral panel?
I know my Drs are lousy - they've been in special measures for at least 2 rounds and the good Drs we had left, but... I can't seem to get individual B vits tested. What's your secret, please?
I've seen lots of reports from people on here, saying that finding they have MTHFR mutations doesn't automatically go with needing extra methylated vitamins. As the amount you need is tiny and methylated vitamins are much more available from your food than they are from supplements, if you have a varied and balanced diet, there's a good chance you are getting all you need from that and the supplements are causing a problem because they are adding methylation in excess.
I don't know if I have MTHFR mutations but I do need extra methyl supplements to function so started to use methylfolate with daily 1.5mg hydroxocobalamin injections when I couldn't get enough B12 just from standard 1mg hydroxocobalamin injections and top up methylcobalamin sublinguals.... however I find the best way by far is from broccoli, sprouts, cabbage, that sort of thing, and other green leafy veggies. plus a wide variety of other foods, as they all have "magic compounds" which help with metabolism.
Because I want to avoid folic acid - not great for those with MTHFR and I need to avoid B6 as I'm top of limit and it can cause neuro issues. Nothing exists for what I want! My diet is excellent but you're not just what you eat but what you absorb and I'm coeliac so that's tricky for me despite strict GF diet for over three decades. I tested my levels privately. I thought to test B6 as it has implications for neuro issues.
I see, thank you!
I think maybe the only option is to buy everything you need individually and take them like that. A pain but at least possible.
yes I think so. Thanks for replying.
I tried methyl B12 twice and it made me feel horrible. I will never take it again.
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