Self-injecting 2 ml EOD.: Hi Family... - Pernicious Anaemi...

Pernicious Anaemia Society

32,669 members24,064 posts

Self-injecting 2 ml EOD.

RisingOne profile image
13 Replies

Hi Family….

Has anyone self-injected 2 ml EOD, subcutaneous? If so has there been any adverse reactions, I currently inject 1ml EOD, for about 6 months. PA brought on-by years of taking PPI’s for GERD.

In the beginning I really didn’t know what I was doing I tried, B12, strips, sprays, tablets, patches, tinctures and my GP, knew very little about PA, even though the Prescriptions for the PPI’s my GP prescribed. All tests, folate, D, homocysteine and others were in normal range and still are after nearly a year. Yet, no real improvement.

Thank God, for this site, my GP and I learned more about PA, from you fine folks than anyone!

This site convinced me and my GP to self-inject EOD, I now self-inject, 1ml, EOD, SUBCUTANEOUS.

That is why I ask if self-injecting, 2ml, EOD, could help or hurt, would speed recovery, it is sooooo slow…I thank God and this site and for all my improvement and education on PA.

Written by
RisingOne profile image
RisingOne
To view profiles and participate in discussions please or .
Read more about...
13 Replies
wedgewood profile image
wedgewood

I believe that injecting into fat layer ( sub -cut ) will slow down the effect . And will be released slowly . Try injecting I.M. ( into the thighs , the Vastus Lateralis muscle ) Use a 26 x 1inch needle . With this method the medication is immediately in the blood , unlike sub-cut .

RisingOne profile image
RisingOne in reply towedgewood

Thanks wedgewood for your advice, appreciated.

B12life profile image
B12life

I agree with wedgewood, do IM and for the reasons wedgewood specified. If you do cyano, do 1ml every day. Because I exercise more now, I do 2 shots IM a day. One in the morning and one at night. This is to spread out the doses avoid peeing out the excess.

I didn’t start heavy exercise until 2 years into it and I will deplete and have if I don’t increase my dose. I have had my kidney and liver function tested. The reason I mention that is because as long as there are not any underlying kidney or liver problems, b12 is not toxic. So you should be ok to do 2ml, but best to spread it out, perhaps try doing daily shots.

Frank77 profile image
Frank77

yes i think Wedgewood is right about this. I currently inject 2ml IM every other day. Sometimes every day. I have heard that it is not advised to inject so much liquid EOD but I haven’t had any problems with this … so far.

RisingOne profile image
RisingOne in reply toFrank77

Thanks Frank77, for your much needed advice.

Orchard33 profile image
Orchard33

I am told by a retired medic friend that 2ml can be injected subc. but no more than 2ml.

RisingOne profile image
RisingOne in reply toOrchard33

Orchard, that info, confirms my research. Thank you.

Blais profile image
Blais

I have always injected into muscle but recently was advised to inject SC. I found it less effective but I’m not injecting every day. Once a week atm with a view to once a month in future

Nackapan profile image
Nackapan in reply toBlais

That's interesting .I do both .

The only difference I find is it goes in quicker IM

But leaves quicker too !

I've been having both for over 2 years now

Vitali-ep profile image
Vitali-ep

2ml is fine, I do either 1ml or 2ml IM. the only issue with 2ml is that it is a lot of liquid in one shot.

I believe would be better to do 1ml every day vrs 2ml EOD.

RisingOne profile image
RisingOne in reply toVitali-ep

Thanks for your help.

Nackapan profile image
Nackapan

I personally wouldn't. 2ml is alot to give sc.

You can only absorb so much anyhow.

Just kerp going EOD

It takes time

RisingOne profile image
RisingOne in reply toNackapan

Once again Nackapan Thanks for all your help and advice👏👏👏👏

Not what you're looking for?

You may also like...

Follow-up EOD injections

Hi Guys and Gals: The response and advice to my last post, should I continue EOD B12 1ml. Was so...
RisingOne profile image

When to switch from EOD to weekly or twice weekly?

Hi Family, this site has been more helpful than my GP and anyone else! Thank you all.. I’ve been...
RisingOne profile image

Taking B12 injections daily.

Hi Guys and Girls, This site has been a tremendous help and blessing for me and my GP, who knew...
RisingOne profile image

What is if any, the proper amount of B12 to self inject. 1ml, once a week, 2ml, once a week or 0.5ml every day. Twice a day, 0.3ml, for PA?

This site has been a tremendous help for me! I have been self- injecting 1ml of B12 subcutaneous...
RisingOne profile image

Fewer Injections, more injections or stay the course? Please advise.

I have been injecting 1 ml of methylcobalamin and cyanocobalamin, eod, alternatively for about a...
RisingOne profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.