B12 injections and T3 (thyroid hormone) - Pernicious Anaemi...

Pernicious Anaemia Society

32,669 members24,064 posts

B12 injections and T3 (thyroid hormone)

rogergee profile image
12 Replies

Morning all.

Asking over here first...

Does anybody have knowledge (or even experience) of whether starting on the B12 injections can kick-start the body's system into doing T3 conversion when it was little able to do that before?

And also, does PA come under endocrinology?

Thanks in advance

rogergee

Written by
rogergee profile image
rogergee
To view profiles and participate in discussions please or .
Read more about...
12 Replies
jade_s profile image
jade_s

PA does not come under endocrinology. Usually hematology, neurology, or gastroenterology.

I don't have any references on it increasing T3 conversion but I wouldn't doubt it. B12D can create a state of severe illness and lots of processes could be affected by that. In my case, b12d created severe "intolerance" to thyroid meds, and attempting to increase the measly dose i could tolerate affected my nerves.

Can you share some context? :)

davina70 profile image
davina70 in reply tojade_s

How did this intolerance manifest itself Jade I’ve been having palpitations for the last year I take thyroxin and have PA ..,?

jade_s profile image
jade_s in reply todavina70

It caused numbness and severe burning. I had palps as well but this could have been due to low thyroid. I see in your TUK post you mention that your dose was reduced - it could very well be from that. You might also need T3. How often do you get B12 injections? You might need more! I have to do them daily even after 6 years.

Here is my post describing what happened when I tried to raise my levo dose while B12 deficient: healthunlocked.com/pasoc/po...

davina70 profile image
davina70 in reply tojade_s

Thanks Jade just been to give blood have a cancellation to finally see an endo on Thursday watch this space !

jade_s profile image
jade_s in reply todavina70

Good luck! :)

rogergee profile image
rogergee in reply tojade_s

Crikey, that sounds difficult for you. Thanks for the info.

Pickle500 profile image
Pickle500

I don't know much about t3 conversion, but about a year before I become severely b12 deficient Doctors found a nodule on my thyroid. This was found following a routine scan after the appearance of a parotid gland tumour.

Because the thyroid nodule was 'indeterminate' for Cancer (i.e. they couldn't say if it was or wasn't C based on a FNA biopsy) they removed half the thyroid at the same time as the parotid gland tumour.

This was in August 2020 and by April 2021 I was on my knees with B12 deficiency. I had been to the GP in March 2020 with symptoms--and even said I wondered if the heat in my body and pins and needles related to the thyroid--and they didn't like that. And told me it was stress.

At no point did any GP raise the issue or test for B12 after removing half my thyroid.

I don't know if this is helpful.

rogergee profile image
rogergee in reply toPickle500

Thank you for that. I hope you've revovered well from everything.

Gambit62 profile image
Gambit62Administrator

I honestly don't know about interactions between thyroid hormones and B12 though it isn't uncommon for people reporting that they need to reduce thyroid medication when they start B12 injections. This may be because some processes that needed both B12 and thyroid hormones start running more efficiently and start using less of the thyroid hormones as a result.

rogergee profile image
rogergee in reply toGambit62

Thanks Gambit62. I hadn't read iit anywhere before asking on here. I can imagine it's another area that's a nightmare via the NHS to juggle to get right for people.

WhyAmISoTired profile image
WhyAmISoTired

Starting on B12 injections didn't affect my t4 to t3 conversion.

However, my tsh increased immediately after starting injections, and other thyroid hormones decreased, so my levothyroxine dose was increased. Once all the tuning was complete, I started feeling much better.

rogergee profile image
rogergee in reply toWhyAmISoTired

Thanks for this. It's very interesting. I suspect it's something that isn't very easily addressed for some people, especially those needing T3 too.

Not what you're looking for?

You may also like...

B12 injections and Acne

Ive read that b12 injections can cause acne and rough skin (sandy paper feeling). I'd rather have...

B12 injections and flushing

After a long time of trying to figure out what has been causing my skin to flush, I am now fairly...
Alpaca24 profile image

B12 injections

Hello, I wonder if someone can advise - I have been having Vit B12 injections for the past two...
glacommare profile image

B12 injections

Does anyone know where I can get B12 injections to do myself? I think there may be somewhere in...
Barb1949 profile image

B12 Injections

Hi, I've been diagnosed with B12 Deficiency & am starting Injections at the GPs this Friday. I'm a...

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.