Long Covid- are they still missing a... - Pernicious Anaemi...

Pernicious Anaemia Society

31,973 members23,121 posts

Long Covid- are they still missing a link with B12 deficiency ?

Cherylclaire profile image
CherylclaireForum Support
25 Replies

In the Mirror today, on the medical page, there is an article about how long covid can affect the way your brain works.

"It wasn't long after the pandemic started that we realised coronavirus targets not only the lungs, but the heart, the brain and other vital organs. The effect on the brain was particularly puzzling..."

Patients had severe depression, hallucinations, paranoia, brain fog, anxiety, unable to think straight or hold onto memories, fumbling for words.....

Link made to those with traumatic brain injuries, HIV - yet no mention of B12 deficiency...could this be the missing piece of the puzzle ?

Research has shown that DMB can be a useful covid treatment for hospitalised patients: vitamin D, magnesium, vitamin B. Singapore studies showing patients treated with these will have less severe symptoms and significant reduction in their need for oxygen. ("Be Well: A Potential Role for Vitamin B in Covid-19")

Martyn Hooper (Pernicious Anaemia Society founder) has made the comparison between symptoms of long covid and PA - and alerted medical experts to this similarity.

It does look strikingly familiar, doesn't it ?

Written by
Cherylclaire profile image
Cherylclaire
Forum Support
To view profiles and participate in discussions please or .
Read more about...
25 Replies

Some weeks ago I read adelina Chalmers recovery from long covid. B12 injections, she was 38 business consultant ( I think) and from Wales.

bookish profile image
bookish in reply to

Thanks for that, I've just found this cambridgeindependent.co.uk/.... Really useful, cheers.

Nackapan profile image
Nackapan in reply to bookish

Yes a remarkable story.I have read that.

Again levels deemed normal with Gp

Awful what's going on

Cherylclaire profile image
CherylclaireForum Support in reply to

I am now quite confused after trying to follow the article:

Adelina Chalmers, six months after having believed herself fully recovered from being hospitalised with covid, experienced long covid.

Later, Dr Klein of Nuffield Hospital, in discussing her case, said that PA and covid was a nasty combination.

So did she have undetected PA before getting covid - or did covid somehow bring on PA ?

If hospital treatment had depleted her B12, why is PA being discussed and not B12 deficiency ?

in reply to Cherylclaire

Who knows ?

Could be a combination of both, although I suspect she was on the lower side, along with Iron .... which seems to go together. Unless she had blood tests for b12 prior to catching covid (highly unlikely) no one will know.

The trouble with b12 its very sneaky at first and you might think you are just having an off day below par,

It's not really noticeable until things become obvious

The body and brain are letting you down. How many times I thought perhaps I was over doing things, and just needed to rest a bit more.

Another relative thirty year old had the 1st covid jab and developed blood clots, was hospitalised for two weeks. He has been referred to a haematologist!

But since then his father was admitted too hospital with pneumonia, and they discovered he had P.A.

He has also a blood clot ! Now all his off springs are having tests. So I think there might be a connection with covid, even the covid jab affecting b12.

What I find very disturbing is the fact that B12 deficiency is far far worse than most deficiencies !

Yet is so overlooked with G.Ps and even treatment is some what abysmal.

One thing with covid and long covid you are hearing more more people being treated with b12 injections

In the hope they improve.

Cherylclaire profile image
CherylclaireForum Support in reply to

......and yet B12 injections stopped for so many when covid started, putting already vulnerable people at greater risk - ??? No wonder I am confused.

in reply to Cherylclaire

It makes you wonder how many existing P.A. (B12D.) sufferers had a worse outcome !

in reply to Cherylclaire

Another website with more information regarding b12 deficiency.hindawi.com b12 deficiency.

There are quite a few reports one concerning the covid injection and a young female.

Hamayeshguy profile image
Hamayeshguy in reply to

Never think this ignorance and misinformation regarding b12 issues is accidental! As no public health issues is accidental in political world!

Nackapan profile image
Nackapan

Yes very similar. Also icve read covid patients in hospital have low b12 snd vit d levels.

Pity that article did not mention b12

Surly it must be looked into and trigger research

deniseinmilden profile image
deniseinmilden

Hi! Thank you for this!

It's been said by lots of us with B12d but, like with treatment for borderline people and giving enough treatment for sufferers, it seems, stupidly, to fall on deaf ears (there's none so deaf as those who won't listen)!

CG12345 profile image
CG12345

Apprently COVID affects yours methylation pathways - if I remember right it both burns through b12 and folate quicker but also it’s impact on the body requires the body to have more than usual in store. When I had Covid, twice i started to take a bit of a dip and twice I gave myself a b12 injection and felt much better. Of course can’t say if in my case it was a placebo or not but it would make sense that it helped.

My acupuncturist had been using b12 injections for her long Covid patients also to great effect.

Sleepybunny profile image
Sleepybunny

Link to PAS news item about Long Covid and B12 deficiency

pernicious-anaemia-society....

response to BMJ article which mentions Covid and B12

bmj.com/content/370/bmj.m30...

WhyAmISoTired profile image
WhyAmISoTired

Completely anecdotally, i thought I had long COVID (and I did: my fatigue got much worse after getting sick, and I had a cough for 8 months!) but last year I discovered a long term b12 deficiency. My fatigue has been so much better since I started addressing it.

WhyAmISoTired profile image
WhyAmISoTired in reply to WhyAmISoTired

However, my partner also had long COVID, and his b12 levels are excellent. It's likely that what we call long COVID is actually a bunch of different issues put together.

Sleepybunny profile image
Sleepybunny in reply to WhyAmISoTired

Thought I'd just add that people can show severe symptoms of B12 deficiency with a serum B12 result that is well within normal range (from personal experience).

WhyAmISoTired profile image
WhyAmISoTired in reply to Sleepybunny

I am aware of that, but his B12 result was over 600, so I think that's good?

Sleepybunny profile image
Sleepybunny in reply to WhyAmISoTired

That does seem a good level.

It is possible to have Functional B12 deficiency where there's plenty of B12 in the blood but it's not getting to where it's needed in the cells.

Functional B12 deficiency is mentioned in Point 5 in this link below. Some info may be UK specific.

b12deficiency.info/b12-writ...

Functional B12 deficiency is also mentioned in this NHS link.

nhs.uk/conditions/vitamin-b...

If he's in UK and he has the symptoms of B12 deficiency, NHS should treat him.

Summary of BSH Cobalamin and Folate Guidelines

pernicious-anaemia-society....

BMJ B12 article

bmj.com/content/349/bmj.g5226

Emphasises need to treat patients who are symptomatic even if their B12 level is within range.

I'm not medically trained.

WhyAmISoTired profile image
WhyAmISoTired in reply to Sleepybunny

At this point his main issue is post-exertional fatigue, which could be due to so many things... perhaps he should get an active b12 test though.

Sleepybunny profile image
Sleepybunny in reply to WhyAmISoTired

Homocysteine, MMA and Active B12 (Holotranscobalamin) can all help to diagnose B12 deficiency when serum B12 is normal range.

Angie47 profile image
Angie47

I know when I had my first covid injection it bought on my B12 symptoms and I did report it to the relevant NHS website then when I got covid I was pretty certain I had it even before the test confirmed it

as my B12 symptoms were a lot worse!!!

KEFNB profile image
KEFNB

Also, Long Covid and Chronic Fatigue Syndrome are similar. Dr Bruce Patterson is doing a lot of research on it. There was an article on PubMed that showed how CFS Patients did better the more B12 they took. If memory serves, the ones who fared best injected three times weekly and took oral B12.

lambuth_eagle profile image
lambuth_eagle

I had COVID in April 2020 (yes, early in the pandemic for the US). The exhaustion lingered for months and I never really got back to fully energy level. Smell and taste affected for 10 months. Skip ahead a year to May 2021 and I began having neurological symptoms that lead to a PA diagnosis. I can’t figure out if the already low B12 made me more susceptible to COVID or if COVID led to the PA. My theory is that I was already B12 deficient but not to the point of symptoms and COVID just sped things along.

Hamayeshguy profile image
Hamayeshguy in reply to lambuth_eagle

And b12 deficiency patients can't make enough antibody for most disease. And since covid is so contagious it can affect any person with PA or b12 deficiency. But remember flu still kills more than covid but no one knows why there is no restriction for that yet!

Sleepybunny profile image
Sleepybunny

I found a couple of interesting articles when I searched online for "long covid B12 deficiency research".

You may also like...

B12 Deficiency and Covid

https://www.cambridgeindependent.co.uk/news/long-covid-patient-in-cambridge-tells-how-simple-treatme

Long Covid similarities to B12 deficiency

I was just reading through a description of long Covid and was struck by the similarities to B12...

NICE CKS link about B12 deficiency symptoms

issue with one comment. For example it say that severe neuropathy does not occur with folate...

B12 and iron deficiency link?

hemoccult test was negative. It is probable that severe intramedullary destruction and hemolysis of...

With normal levels of b12 can you still be deficient

needles, numbness in arms, lack of fine motor skills, brain fog, tingling on tip of tongue, now...