Does everyone feel the benefit of B12 injections. I never feel any benefit at all. I’m still always soooooo tired and my serum levels are high. Doctor won’t drop under 3 mts. Between injections. They ALL do what they’re told. Don’t listen to patients! They go by the book. My daughter gets hers every 8 weeks she’s 55 yrs. I am 78yrs I get mine every 12 weeks both have high serum levels, how does that work!!!
Gezabelle
The first time I noticed was after a maintenance dose and realising that at 1600 I wasn't falling asleep and totally exhausted.A friend commented once, after giving me a lift to the surgery, that I'd come out of the surgery after my shot with a spring in my step.
The effect would only last a couple of days though.
Serum B12 is at best a difficult test to interpret after you have had a loading shot as the conditions of the normal range are totally changed by the fact that the first injection raises your serum B12 levels off the scale and then they gradually reduce at rates that can vary significantly. I don't think anyone has done a study of how variations in time taken to remove B12 (which can be years) relate to symptoms returning. Its easier to follow the quantitative measures than it is to look at quantitative measures like how a person feels.
Hi,
I'm wondering if you are getting enough B12.
I need far more B12 than NHS is willing to give me so I had to resort to treating myself.
"Doctor won’t drop under 3 mts"
Have you asked GP why they won't give injections more frequently?
Knowing why they are reluctant can help you argue effectively to get them more often.
If you have a PA diagnosis or suspect you have PA then worth joining and talking to PAS who can offer support and pass on useful info.
PAS (Pernicious Anaemia Society)
Based in Wales, UK.
pernicious-anaemia-society....
There is a helpline number that PAS members can ring.
Have you considered writing a short, polite letter to GP asking for injections more often and backed up with some evidence supporting your request?
See letter writing link below.
Letters to GPs about B12 deficiency
b12deficiency.info/b12-writ...
If you have neuro symptoms, my understanding of BNF (British National Formulary) guidance is that you should be on injections every 2 months.
See section for those with "neurological involvement" in link below.
BNF Hydroxocobalamin
bnf.nice.org.uk/drug/hydrox...
GP can find this information in their BNF book Chapter 9 Section 1.2
If you find out why the GP is reluctant to give you injections more often, come back to the forum and I'm sure people will be able to pass on other useful information to you.
Rule is every 3mts my levels are good. End of. They know nothing about B12. So frustrating. I’m trying to get B12 privately.
Is it possible that your tiredness is being caused by something other than your b12 deficiency? Have you had a full blood count, liver and kidney function tests, diabetes test, thyroid test and iron levels checked? Has your heart function been checked out?
Was your vit d, folate, iron all normal?What was your b12 level before any injections?
Yes. I think intrinsic factor is low.
Has anyone had insomnia from B12 injections?
About German online Pharmacies. — If they follow pharmaceutical rules rules,they are not allowed to supply U.K. with B12 ampoules! 
Silent Reflux and B12 Deficiency- Any Link?
