How long does the "depot" last of a B12 injection?

[Cetus]

The hydroxocobalamin injections I have seen all say "DEPOT". Does this mean an intramuscular injection of B12 forms a sort of "nodule" which dissipates slowly over a long period. Perhaps days? Could it be as long as weeks?

I had the idea that B12 was rapidly absorbed by the flow of blood in the muscle and was largely gone within 10 minutes. Is this incorrect?

[Nackapan]

'Depot' to my knowledge just means Hydroxocobalamin . Ftom the Gerndn pharmacies

You are correct in thinking it injects directly into our bloodstream

[Gambit62 Administrator]

I think the medical definition of a depot injection is that it is one that results in the active ingredient being available for a long time reducing the frequency for treatmentmedical-dictionary.thefreed...

There are some problems with the use in relation to B12 because, as we know - it does result in B12 staying in the blood for longer but that doesn't necessarily mean that the B12 is effective.

[ACritical in reply to Gambit62]

Is that the reason that so many of us have a high serum level after regular injections but still feel we need more frequent ones to keep on top of the constantly reappearing of certain symptoms? The high serum level isn’t all effective anymore?

[Gambit62 Administrator in reply to ACritical]

reason why some need more frequent injections despite high serum B12 levels isn't known - could be a number of reasons - some research going on at the moment sponsored by the PAS.