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Serum B12 result

Blackpanther46 profile image
13 Replies

Hello , I finally have had the GP test after the low active B12 test at 62 from medichecks.

It says B12 - 381 range 120-625

Folate 11.8

Ferritin 93 range 11-307

So I’m thinking my symptoms are menopausal now rather than B12 but what do you think about these results please ?

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Blackpanther46
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13 Replies
Gambit62 profile image
Gambit62Administrator

It is really difficult to interpret serum B12 from a single test. If you have an absorption problem you will be looking for levels that are falling significant >20% over time.This is because people maintain serum B12 levels at the point that is right for them using stores in the liver but if you have an absorption problem this mechanism doesn't work and levels start to fall. The exact level varies considerably from person to person so although your result is well into the normal range that doesn't mean that it is the right result for you - though being well into the range does make it unlikely so would be a good idea to look at other options, such as menopause.

Nackapan profile image
Nackapan

They look good to me. Strange the active b12 low in range though as that's what you can use?

Did they also test vitamin D ?

Beware of putting symptoms down to the menopause

I did that.

Go by your symptoms.

Now at least you have baseline as gsmbit62 says we all function at different levels so on another test in the future it will show if levels are declining.

Hopefully other tests will be done too depending on your symptoms

T C

Sleepybunny profile image
Sleepybunny

Hi,

If you think your symptoms are related to menopause, perhaps GP can order some hormone tests.

On one of your other threads I think I mentioned that UK guidelines suggest treating patients who have the symptoms of B12 deficiency even if serum B12 results are within normal range.

B12 - 381 range 120-625

Do you know the units for the above test...was it ng/L?

I had severe B12 deficiency symptoms with most B12 results between 300 - 500 ng/L

Do your symptoms match those of B12 deficiency?

Symptoms of B12 Deficiency

pernicious-anaemia-society....

pernicious-anaemia-society....

b12deficiency.info/signs-an...

b12d.org/admin/healthcheck/...

cks.nice.org.uk/topics/anae...

Symptoms of Peripheral Neuropathy (damage to peripheral nerves)

nhs.uk/conditions/periphera...

Peripheral neuropathy can be associated with B12 deficiency and sometimes with folate deficiency.

Neurological Consequences of B12 Deficiency

PAS news item

pernicious-anaemia-society....

PAS article about SACD, sub acute combined degeneration of the spinal cord

pernicious-anaemia-society....

Blog post from Martyn Hooper's blog, mentions SACD

martynhooper.com/2010/09/21...

B12 deficiency and mental health symptoms

b12deficiency.info/mental-h...

stichtingb12tekort.nl/engli...

I could not get treatment for my typical B12 deficiency symptoms due to most results being within normal range and I got to the point of dementia type symptoms and spinal symptoms.

If you feel that your symptoms fit B12 deficiency, try to get GP to exclude other possible conditions that could cause similar symptoms.

There may be useful info in my replies on your previous thread.

Blackpanther46 profile image
Blackpanther46

I thought they looked ok too . Vit D was tested before and good at 110 .

Menopausal symptoms aren’t accurate on blood tests but I’m sure it’s hormones a lot . I don’t have cows milk due to intolerance so I’m diary free but eat meat though so could that cause dietary deficiency do you think ?

Blackpanther46 profile image
Blackpanther46

Hi , yes ng/L . Yes I remember you saying that but my doc won’t do anymore tests and even if I paid for the private MMA one they probably wouldn’t treat me with injections.

Symptoms are mouth ulcers from time to time but I also get those when my thyroid is out . I get tinnitus but also hypo and meno symptom . Exhausted etc also hormonal . I don’t feel that I have definitely got those B12 deficiency symptoms but some do sound like it . I really am not sure what to think .

Sleepybunny profile image
Sleepybunny in reply toBlackpanther46

Do you have any other symptoms in or around your mouth?

Glossitis (sore, inflamed tongue ) is a typical symptom of B12 deficiency ( and folate deficiency).

Link to thread where signs of B12 deficiency in the mouth are discussed

healthunlocked.com/pasoc/po...

Blackpanther46 profile image
Blackpanther46 in reply toSleepybunny

Sometimes but not always sore tongue . It comes and goes .

Sleepybunny profile image
Sleepybunny in reply toBlackpanther46

If the sore tongue is intermittent then I suggest you take a photo when that symptoms shows.

Does your GP know you get a sore tongue?

Do you have what look like bite marks around edge of tongue?

Splits in tongue?

Pale yellow tongue?

Swollen/enlarged tongue?

Sore spots at corner of mouth?

See link to thread about mouth symptoms in my other reply for more info.

I used to get pins and needles in my tongue and teeth...

Some people report a burning sensation in their tongue.

Link to a thread where a tongue picture was posted

healthunlocked.com/pasoc/po...

Blackpanther46 profile image
Blackpanther46 in reply toSleepybunny

Yes good idea. No the doctor doesn’t know it’s never seems that bad enough to tell them . No split marks but pale colour and bite marks. Again this can be menopausal or hypothyroidism. No swelling or sore corners of mouth .

Argh puns and needles in teeth and tongue that sounds horrible!

Blackpanther46 profile image
Blackpanther46

I don’t really have those neurological symptoms apart from blurred vision a bit but again that can be menopausal

Im getting eyes tested next week anyway .

Sleepybunny profile image
Sleepybunny in reply toBlackpanther46

Neuro symptoms can include...

tingling

numbness

pins and needles

electric shock sensations

burning sensations

insect crawling sensation (formication)

I used to get the sensation of water trickling down my spine.

tinnitus

muscle twitches,

muscle fasciculations (looks like muscles are rippling under the skin)

flickering eyelids

restless legs syndrome RLS

periodic limb movements (jerks that often affect legs/arms,can affect fingers, toes, head)

vertigo

migraine

clumsiness

dropping things

bumping into things

strange gait (unusual way of walking)

foot drop

word finding problems, (nominal aphasia)

balance issues

brainfog

confusion

proprioception problems (problems with awareness of body in space)

memory problems

lost of ability to do mental arithmetic

strange behaviour eg putting car keys in the fridge, boiling the kettle without any water in it

There are many other possible neuro symptoms that can be associated with B12 deficiency.

See links to symptoms lists in other reply.

KEFNB profile image
KEFNB

With a low active B12 I would suggest a trial if B12 injections. My serum B12 was greater than 2000. (I was taking sub lingual B12) and was exhausted with tingling in toes and fingers. My MCV was 102. My doctor didn’t have an explanation. My friend suggested that I try one of her injections and noted that it takes her about four days to feel improvement. Well, in four days I was remarkably better, but it only lasted for about three days. Currently I take an injection every three or four days. I am a new person.

Blackpanther46 profile image
Blackpanther46

Thankyou . I only get tinnitus brain fog memory problems forgetfulness but also those are meno symptoms. I don’t have any of the other symptoms.

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