Reaction to loading injections - Pernicious Anaemi...

Pernicious Anaemia Society

31,973 members23,121 posts

Reaction to loading injections

MandiJ64 profile image
8 Replies

Hi. I had very low b12, 50, and must have had low for about 25 years as I’d had a lot of symptoms, especially when I was “run down” such as fatigue, sore tongue, low mood, cold symptoms. I have been on stomach acid reducing tablets for about that time and only just been tested for b12.

I had the loading injections and felt a lot better, more energetic and breathing better, but about 3 weeks after the injections I started to get all the symptoms back: bad cold, tongue sore, very, very lethargic, depressed, and this lasted nearly 4 weeks (before it used to last a couple of days and go with a lot of sleep). Doctor couldn’t see it was related to the injections but it’s too much of a coincidence to me. I am now feeling a lot better and got my new “bounce” back.

Has anyone else had a reaction to their loading injections like that?

Written by
MandiJ64 profile image
MandiJ64
To view profiles and participate in discussions please or .
Read more about...
8 Replies
Nackapan profile image
Nackapan

So the loadng doses helped you.Usually after 3 weeks if the symptoms back you need injections every few weeks

What gave you your 'bounce back?

Was it another b12 injections as not clear.

Yiuf medication probably reduced yiur b12

MandiJ64 profile image
MandiJ64 in reply to Nackapan

Yes it was my medication that reduce it. My bounce just came back without any further B12, once my body had recovered from all the symptoms. Dr has put me down for 12 week injections so next one in August. I was thinking my body had reacted to going from 50 to high after being low for so long, wondering if anyone else had experienced this

Nackapan profile image
Nackapan in reply to MandiJ64

Oh yes it will have reacted. Woken up so many nerves. Marvelous to have such a good quick outcome.

MandiJ64 profile image
MandiJ64 in reply to Nackapan

Thanks. Hopefully those 4 weeks feeling s**t won’t be repeated

charks profile image
charks

I'm sorry but I don't quite understand the situation. Did your symptoms resolve with another B12 injection? Or did they go without further treatment?

MandiJ64 profile image
MandiJ64

Went without treatment

Showgem profile image
Showgem

Your b12 level of 50 was extremely low to have recovered from so quickly unless it was your active b12 that was tested. I pleased that you feel well.

MandiJ64 profile image
MandiJ64

Thanks

You may also like...

Reactions to loading doses

I'm on loading doses for B12 deficiency 1 injection a week for 6 weeks, then a blood test, then I...

Loading injections

pernicious anaemia so I didn’t need loading injections. I explained I take a b12 100% dose tablet...

15 year old - Loading Injections

started loading injections, her reading was 85. She had been suffering for months, is now very...

B12 injection reaction

I’m in the UK, I had my first B12 injection yesterday and today I’m feeling very dizzy and unstable...

Reaction to injections and tablets

to do. I've had blood test which shows my b12 is really low, dr called me in for injections. On the...