Can these results mean I may need to think I have PA?

[Soundwell1]

Oct 2019 uk

Vit b12 247 ng/l. (145 - 910 ng/l)

Folate 8.6 ug/l (3.00 - 20ug/l)

Ferritin 48 (10 - 150ug/l)

Vit D result 26th May 2020,

66.7.

I also take thyroxine for hypothyroid and have osteoporosis and type 2 for 50 years.

Can anyone help to tell me if I'm going like my mother who had pa.???

[JanD236]

Your B12 results are fine and are in the normal range. Is there any reason why you think you have PA?

[Sleepybunny]

Hi.

Are you symptomatic for B12 deficiency?

Symptoms of B12 Deficiency

pernicious-anaemia-society....

b12deficiency.info/signs-an...

b12d.org/admin/healthcheck/...

If you have symptoms consistent with b12 deficiency plus a family history of PA then I would hope your GP would test you for PA.

If you suspect PA, I recommend joining PAS who can offer support and info.

PAS (Pernicious Anaemia Society)

Based in Wales, UK.

pernicious-anaemia-society....

There is a helpline number that PAS members can ring.

PAS support groups in UK

pernicious-anaemia-society....

No meetings during pandemic.

Blog post about how PAS can support PAS members seeking PA diagnosis

martynhooper.com/2017/06/24...

B12d.org have some online meetings during pandemic.

b12d.org/event

There are many possible causes of B12 deficiency besides PA eg diet, Coeliac disease, H pylori infection, fish tapeworm infection, Crohn's disease plus others.

Link about "What to do next" if B12 deficiency suspected

b12deficiency.info/what-to-...

I wrote very detailed replies on another forum thread with links to B12 deficiency symptoms lists, causes of b12 deficiency, info about tests for PA, B12 books, B12 websites, UK B12 documents, letters to GP about B12 deficiency and other B12 info which you might find helpful.

healthunlocked.com/pasoc/po...

From personal experience I know it is possible to have severe B12 deficiency with an in range serum B12 result.

I am not medically trained.

[Seth12345]

Your B12 is in the normal range, but it is still low. I would suggest bumping it up if you can. It won't hurt you to do that.

I'm not a doctor.

[Soundwell1 in reply to Seth12345]

Thanks. I bumped it up to 999 3 years ago but I didn't feel any better with fatigue memory issues and dizziness and double vision and headaches.

[fbirder in reply to Soundwell1]

If you got your B12 levels up that high with tablets then it means you do not have PA. It's also extremely unlikely that your symptoms are caused by a B12 deficiency.

[Soundwell1 in reply to fbirder]

Thank you.

[Sleepybunny]

It is possible to have normal range or even high levels of B12 in the blood and still have symptoms of B12 deficiency.

Some people can have Functional B12 Deficiency, where there is plenty of B12 in the blood but it's not getting to where it's needed in the cells.

Link about writing to GP if symptomatic for B12 deficiency with in range B12 result

b12deficiency.info/b12-writ...

BMJ B12 article

bmj.com/content/349/bmj.g5226

Emphasises need to treat patients who are symptomatic even if their B12 level is within range.

Articles about Functional B12 Deficiency

academic.oup.com/qjmed/arti...

Article about Serum B12

stichtingb12tekort.nl/weten...

Article is from Dutch website so units of measurement mentioned may vary from those used in UK.

[Soundwell1 in reply to Sleepybunny]

Thanks