PPIS making me not absorb b12 - Pernicious Anaemi...

Pernicious Anaemia Society

31,973 members23,121 posts

PPIS making me not absorb b12

Nanny23 profile image
3 Replies

Hi I have to take a proton pump inhibitor for Barrett’s esophagus. It’s an acid blocker which blocks acid in the intestine. I tried taking other meds to no avail. If I don’t take this drug I could get esophageal cancer. I have to take B 12 injections now. If I don’t my feet get numb. Do the injections work?

Written by
Nanny23 profile image
Nanny23
To view profiles and participate in discussions please or .
Read more about...
3 Replies
wedgewood profile image
wedgewood

Yes , they will work . The injections by-pass your stomach , so you will get your B12 . But the PPI will leave you with low/ no stomach acid ( ( Hypochlorhydria/ Achlorhydria) ) This can result in poor absorbtion of other vitamins and minerals . . It would be good to take a multi vitamin and mineral tablet . Also it’s very important to chew your food really well , as saliva contains enzymes that start the break-down process . . Having smaller meals more often helps also . There are preparations containing other enzymes to help in the break-down of food ( e.g. Solgar digestive enzymes) Look up diets for Achloryhdria. .( but obviously ignore advice to supplement with Betaine HCl )

Stomach acid is needed to keep the stomach flora balanced . Probiotic foods like raw organic sauerkraut ( you can make your own or buy it in health food shops or online ) real yoghurt , kimchi and kefir are very good sources . Probiotic capsules etc can also help , if you don’t like those foods .

Best wishes .

Nanny23 profile image
Nanny23 in reply to wedgewood

Thankyou s much for your help. I really appreciate it.

Ashley820 profile image
Ashley820

I have the same issues. I was found to have low B12 in August when all of the sudden my feet were going numb on top of extreme fatigue, palpitations, and just a feeling of unwell that I’ve never experienced before. I had taken protonix for almost 2 years by then for GERD. I stopped protonix and started weekly B12 injections. I was seeing a major improvement in some symptoms in about 3 months, but still experiencing numbness regularly. Then in December, my GERD flared horribly again and I had to go back on the protonix as it was unbearable with any other medication that I tried. My GI specialist thinks I’ll need to be on it long term. I’m still taking weekly injections and have numbness only in my big toe and the part of my foot directly touching it maybe once every one to two weeks which is a huge improvement for me. The injections do work. My primary doctor wanted me to start spacing them out to monthly, but I’m not able to yet without seeing an increase in numbness. I don’t know if/when I’ll be able to do that now that I’ve restarted the protonix. Don’t get frustrated if you don’t see improvement right away. My other symptoms were the first to improve but the numbness took much longer. My neurologist, who after much testing found that I have small fiber neuropathy from the low b12, said that nerve repair takes time and patience and that I shouldn’t get discouraged before the 6-12 month mark. Good luck to you!

You may also like...

Problem absorbing/ storing b12

Hi, does any one have any idea why I might not be absorbing/ storing b12, i recently decided to try...

b12 injections making me worse

came back as having a serum b12 of 73 so my doctor started me on b12 injections. I have had 3 out...

B12 makes me anxious and jittery

because I often work at home. My physical symptoms improve constantly. Don't have all the wired...

If B12 cannot be boosted by diet, can folate tablets be absorbed by the body?

cannot get the required B12 from diet, so I have injections. But I've seen on forums that B12 is...

Why does B12 now make me really ill

back on my injections, I get really bad, side effects. It is making me feel that it is just too...