B12 IM hydro can I use IM meth? - Pernicious Anaemi...

Pernicious Anaemia Society

31,973 members23,121 posts

B12 IM hydro can I use IM meth?

Zoe99 profile image
12 Replies

Hi my supplier has run out of b12 IM hydro this can often happen. Has anyone experienced the differences with B12 meth and can tell me about them?. Was wondering if I could use meth when hydro is out of stock I know it's more expensive? Many thanks.

Written by
Zoe99 profile image
Zoe99
To view profiles and participate in discussions please or .
Read more about...
12 Replies
wedgewood profile image
wedgewood

Yes of course you can use Methylcobalamin instead of Hydroxocobamalin . Some people think it’s better than Hydroxocobalamin. I have used both and found no difference , except the price .

fbirder profile image
fbirder

I've tried IM methylcobalamin - just once. It made me feel terrible I was agitated and irritable. I just felt 'wrong'. I gave away the rest of those ampoules.

YogiGreg profile image
YogiGreg

I've also tried Methylcobalamin, twice! Never again. Felt awful. But everyone is different. Hydroxocobalamin or Cyanocobalamin work for me.

Zoe99 profile image
Zoe99 in reply to YogiGreg

Hi was it the day after you felt bad as I have seen some comments on what they describe as the meth 'hangover 'but then the following day it's worn off?

YogiGreg profile image
YogiGreg in reply to Zoe99

The "meth hangover" the first time for me lasted a week, the 2nd time about 8 days. Unpleasant to say the least.

Zoe99 profile image
Zoe99 in reply to YogiGreg

Thanks for your reply. What were your hangover symptoms? I ask as have chronic IBS and don't want to make it worse.

YogiGreg profile image
YogiGreg in reply to Zoe99

Anxiety, panicky, confusion, tinnitus, fuzzy vision, irritability. :) That doesn't mean it won't affect you in other ways, and it's entirely possible that ypu will do really well on Methyl like many other people do. :)

Zoe99 profile image
Zoe99 in reply to YogiGreg

Thanks for all your help.

Catman1 profile image
Catman1

I use methylcobalamin and find it really good if any help. Best of luck

fbirder profile image
fbirder

There is no reason why methylcobalamin should be any better than any other type - b12science.com/B12Science/D...

Elijahhawk profile image
Elijahhawk in reply to fbirder

On the NIH site, there's actually more research papers on methylcobalamin than hydroxocobalamin. What does that tell you? That doesn't indicate superiority as much as, I guess, scientists just chasing their respective tails.

I don't support claims of superiority of one form over another (exceptions for specific medical indications) and I also don't support diminishing one over the others.

I personally know some people that regularly use methylcobalamin without side effects. Doesn't take away from those that say they have.

My dad was on 25mg (yes, that much) IM every three days for one and a half years without negative side effects. I've been using it regularly for a couple of years without untoward effects.

Love to everyone.

[this post has been edited by Admin]

fbirder profile image
fbirder in reply to Elijahhawk

If you think that the number of publications makes any difference, then Google Scholar has 15,300 citations for methylcobalamin vs 49,800 for cyanocobalamin. Therefore cyanocobalamin is better.

Please show the comparative studies demonstrating that methylcobalamin is better than anything else - comparative studies, published post-2015 when it became known that all forms of B12 are identical when they enter the cell.

Why do you think that saying "There is no reason why methylcobalamin should be any better than any other type" is disparaging?

You may also like...

Where can I buy safe Methyl B12 for UK use?

diagnosed with B12 deficiency. She’s on monthly injections, I’m on 3 monthly, but we SI with hydro...

where can I buy a B12 injection pen

don't know whether to trust the site or their products and am hoping someone knows where I can...

Where can I buy B12 ampoules

Does anyone know where I can purchase some more B12 ampoules - my current supply is rapidly running...

Can B12 IM injection products also go sub cutaneous?

As the title, can I use the injectable products to either go under the skin or into the muscle or...

Start of B12 treatment but can I do exercise?

Really don’t know how to managed my deficiency until my B12 levels improve. Looking for advice on...