Been offered b12 I. M. trial of 2 weeks - Pernicious Anaemi...

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Been offered b12 I. M. trial of 2 weeks

Damseltree profile image
6 Replies

See my previous posts, many neurological symptoms and most of the other symptoms too. But serum b12 in 300s and MMA and HoloTC in the normal range but I don't have the actual figures yet. I have just been told by my private Geriatrician that dispite these result he has persuaded my GP to give me a trial of two weeks b12 injections. The question is will this be long enough to prove PA one way or the other? Or should I press for say three weeks?

Your advice would be helpful.

Thank you in advance.

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Damseltree profile image
Damseltree
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6 Replies
buster_uk profile image
buster_uk

To be honest even with loading doses. It might take months, if not years to feel the benefit. Depends on how long you have been deficient. And what damage was done.

fbirder profile image
fbirder

How many injections over those two weeks?

In the UK the standard protocol is three injections a week for two weeks, then one every two to three months. Most people find that some symptoms improve over those two weeks. Others will take much longer, and some symptoms may never get 100% better.

Having a trial period of injections definitely is the best way to diagnose a deficiency.

Oundle profile image
Oundle in reply to fbirder

NICE guidelines state injections on alternate days until the symptoms stop improving. Two weeks is not enough.

Nackapan profile image
Nackapan

Assuming you ate having a loading dose of 6 injections I think that would be a good trial . I hope it brings a benefit to you.

Damseltree profile image
Damseltree

Thank you for your replies. If the trial is successful I hope I will be offered continued injections as I have serious neurological damage. I will gather my information ready to discuss with the GP.

Sleepybunny profile image
Sleepybunny

Hi,

I wrote detailed replies on a recent thread that may be of interest to you.

healthunlocked.com/pasoc/po...

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