IM vs Subq

[Littledancingtiger]

I don’t know if it’s in my head but I think I feel better after having had an IM injection. I had been doing subq myself.

Why would this be or is it purely a coincidence?

[Nackapan]

I feel better after going back on Im I jections. On the 6 weeks off I took tablets and sublingual spray and was going downhill

So continuing with every other day at present.

[Galixie]

I don't know the reason why, but I also seem to do better on IM injections instead of subcutaneous. I found that I needed quite a bit more B12 when I did subq shots in order to get the same benefit. It doesn't make logical sense, because both forms theoretically work equally. I can only relate that my experience has been better with IM than subq.

[Littledancingtiger in reply to Galixie]

It’s strange isn’t it. I definitely feel better after the IM. Think I’m going to have to swap.

[GastritisB12]

I also feel better on injections. Is it because only about 1% of the sublingual is absorbed?

I read that online somewhere.

That would mean I'm getting only 10 micrograms from the 1000mcg tablet?

[Happysmile]

I only feel benefit from IM. Sub cut doesn’t seem to work for me. I didn’t expect it to be different but it is for me.

[Littledancingtiger in reply to Happysmile]

The difference in me is like night and day and I’m very surprised. A bit gutted as subcut was a lot easier and I was really scared to IM. But if needs must....

[fbirder]

There is no possible reason why IM should be better than SC, or vice versa, assuming they had been performed correctly.

[Littledancingtiger in reply to fbirder]

Thanks I didn’t think so either but I’ve definitely responded better from the last few IM’s I’ve had done so don’t understand it. Could it be possible I need to do the subcut more often? I had been alternating days.

[fbirder in reply to Littledancingtiger]

If the injections are being done properly (i.e. nothing is leaking out) then the whole dose is getting into the body.

The only explanation I can think of is that the SC dose is being absorbed more rapidly than the IM. That would mean that more of it would get excreted in the urine.

[Littledancingtiger in reply to fbirder]

Yes none leaking and no pink tinged skin so it had all gone in. Very strange.