B12 and flying.....: Hi everyone.....I... - Pernicious Anaemi...

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B12 and flying.....

Plucky1976 profile image
6 Replies

Hi everyone.....I’m curious if there is any way flying could affect those of us with b12 issues. The strangest thing happened. I’ve travelled before since self injecting but for some reason the day after I arrived I started feeling major anxiety symptoms. MAJOR. I haven’t had them since the beginning. What could be up? I haven’t changed anything except cut my epsom baths out for the last 2 weeks. I normally have in twice a week and of course this hotel has no tub😳. I’m heading home tomorrow so I will have an injection most definitely but just wondered if anyone else has experienced symptoms after flying. Hope everyone is managing ok😊

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Plucky1976
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Gambit62 profile image
Gambit62Administrator

could be something to it

Not quite flying but about the extreme of space flight

ncbi.nlm.nih.gov/pmc/articl...

Trying to look at genetic factors that could couse health problems.

Didn't go the whole way through the article but did find this ... and there could be more

One carbon metabolism and neuro-ocular health

There is mounting evidence that specific health risks, such as neuro-ocular changes [and increased intracranial pressure (ICP)], are related to disordered one-carbon metabolism involving folate, B12, and Hcy. Approximately 20 % of ISS crew members on space flight missions of 4 months or longer have experienced ocular changes and persistent visual problems on return to Earth. These were correlated with significantly elevated levels of Hcy, methylmalonic acid and cystathionine, along with reduced levels of folate and Vitamin B12 (Zwart et al. 2012). The metabolite data indicate that a significant proportion of crew members may have associated genetic traits that contribute to disturbed one-carbon metabolism. In addition, the metabolic pathway mutation described above has been conclusively linked to the production of oxidative stress and damage associated with coronary artery disease (Vijaya Lakshmi et al. 2011). While the link between space flight-induced ocular changes and altered one-carbon metabolism must be replicated in follow up studies, the existence of such a link may have significant implications, given the altered fluid dynamics known to occur in space flight.

Frank77 profile image
Frank77

That is very interesting. My B12 problems first appeared the day after a long flight to NY. I thought at first I was just having severe jet lag. But the symptoms (brain fog, fatigue) never left. It was only about 6 months later that I discovered that my problem was B12 deficiency, by which time I was in quite a bad way. Since then I have often wondered about this apparent coincidence : why my first ever B12 symptoms appeared literally the day after a long flight. Since I have never seen this particular aspect mentioned on this forum I suppose I put it down to coincidence or a healthy imagination. But now I am not so sure...

Zumbaaaaa profile image
Zumbaaaaa in reply toFrank77

I have had severe symptoms after long haul flights and shorter flight intense fatigue even when injected just prior to flight always wondered whether it was felt by others too.

Plucky1976 profile image
Plucky1976 in reply toZumbaaaaa

I’m wondering if it’s the stress is flying. We don’t realize how tiring it actually is and if I’m stressed severely or physically for any amount of time I start feeling it.

Plucky1976 profile image
Plucky1976 in reply toFrank77

I’m with you on this one. I could never understand why I always felt “weird once up in the air and for a good 24 hrs. afterward. I thought maybe because I was anxious but flying doesn’t give me anxiety. I’ve done it so many times I can’t even count but every time I feel “funny”. I did have an injection when I got home, an epsom salt bath and a nap and woke up to my calves rock hard. So strange! Better this morning but at least the severe anxiety has disappeared. Going to be looking into this a lot more I think!

helvella profile image
helvella

There could be any number of reasons for flying affecting health. I offer a couple of links, one rather old (about 1986), the other a bit more recent. There are bound to be others.

ncbi.nlm.nih.gov/books/NBK2...

ncbi.nlm.nih.gov/books/NBK2...

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