Hi,
I just got the test result for methylmalonic acid in urine:
Creatinine: 1.78 g/l
MMA: 2.6 mg/g creatinine
Since I only see MMA mentioned in nmol/l everywhere, I was wondering if I could convert it to that: 2.6 mg/g * 1.78 g/l = 4.6 mg/l MMA. The molecular weight of MMA is 118.091 g/mol, so 0.0046g/(118.091g/mol) ≈ 3.8*10^-5 mol = 38000 nmol. So my MMA would be 38000 nmol/l, which is obviously wrong. Is it even meaningful to convert from mg/g creatine to nmol/l?
You have 1.78 g of creatinine per L. Which seems high for blood. So I suspect this is a urine test.
The urine test has a reference value of <3.60 mmol/mol creatinine
mayomedicallaboratories.com...
MMA has a relative molecular mass of 104 g/mol. Creatinine has a RMM of 113 g/mol
So your 1.78 g of creatinine = 0.016 mol = 16 mmol
You have 2.6 x 1.78 = 4.6 mg of MMA which = 0.045 mmol. 2.6mg/g x 1.78 g
So your MMA level is 0.002 mmol (MMA) / mol (Creatinine) 0.045 mmol / 16 mol.
Well within limits.
Hi, thanks for the explanation. Are you sure you're calculating mmol/mol and not mmol/mmol? Because the creatine is 0.016 mol, so you'd get 0.045mmol/0.016 mol = 2.8mmol/mol right? Still within range.
D'oh!
Yes you are right. I thought that seemed a bit low.