I posted previously in regards to having issues with being able to drink any amount of alcohol without feeling like I got run over by a truck. Several others posted they also have this issue.
I've been doing some research and alcohol dehydrogenase seems to pop up in several of the articles.
pubs.niaaa.nih.gov/publicat...
So with further research i started taking NAC because appearently cysteine is the rate limiting portion of the formation of glutathione which helps process the toxic by product of alcohol, acetaldehyde.
medium.com/@researchangover...
articles.mercola.com/sites/...
I took jarrows 600 mg of nac, sustained release 3X daily for 10 days before having a drink and low and behold, i was fine.
After further research i found that h pylori, which i had, has an alcohol dehydrogenase relation.
sciencedirect.com/science/a...
So ok, maybe h pylori is why some people with a b12 deficiency have issues with alcohol while others dont.
Further research into my vision issues/brain fog brought up links between alcohol dehydrogenase and retinol (viamin A).
ncbi.nlm.nih.gov/m/pubmed/9...
I started taking vitamin A 2X daily (retinol, not beta carotene kind), and astaxanthin 12 mg both 2X daily(recommended by vitamin shop owner for night blindness issues) and low and behold my vision/blurriness/dizzyness/double vision was better in 5 days. (Note: i thought the vitamin A was 10k iu, so i took 2 daily. later, i realized the vitamin A was 25k iu so at 2X daily that was alot and i dont recommend that much so i scaled back to once a day.)
For whatever reason my energy improved greatly when taking 2X daily and reduced some, not all the way back to prior level with 1X daily. I did not expect that so again i looked it up. This says retinol effects the mitochondria production of ATP (energy).
ncbi.nlm.nih.gov/m/pubmed/1...
ncbi.nlm.nih.gov/pmc/articl...
I believe gambit or fbirder has a background in scientific research. I am wondering if alcohol dehydrogenase or its toxic by product, acetaldehyde, could be the link for lingering symptoms after having b12 injections, for some of us.
Has anyone else taken these suppliments and found they help?