I discovered your site a few weeks ago after recently being diagnosed with PA. I did not know about B12 deficiency, and after my GP diagnosed me in November she arranged for me to have a series of B12 shots. After reading ‘Could It Be B12?’ and ‘What You Need to now About Pernicious Aneamia & Vitamin B12 Deficiency,’ I was enlightened to say the least. Back in 2004 I developed severe neck pain, which then morphed into pins and needles as well as numbness that started in my right toe all the way to my right shoulder. I could not feel that side of my body and my GP at the time sent me straight to a neurologist where I had an MRI and a lesion was found in my C2 (cervical spine). I recovered after six weeks but then developed a few months later severe joint and neuropathic pain. The neuropathic pain with treatment eventually disappeared after 12 months but the joint pain was unbearable. My GP tested my iron levels and they were very low so was told to take FabIron and this did help with my energy levels but little impact on my joint pain. I was referred to an immunologist and had a gallium scan which showed inflammation throughout every joint in my body and was diagnosed with seronegative arthritis. Fast forward a few years and I developed another lesion in my thoracic spine, although my neuro at the time didn’t think it necessary to have a spinal MRI. Instead I had a brain MRI which came back normal and was therefore told I did not have MS. My GP in Melbourne was smart enough to order a Vitamin D test which should my levels to be extremely low so I have been supplementing for about five years and this has made a huge difference in terms of not getting any more colds. I also see a rheumatologist who has officially diagnosed me with demyelinating Sjogrens, however the only dry part of my body is my eyes. Fast forward to the last four years and I still have terrible joint pain as well as developed migraines (I never get headaches), severe nausea, tinnitus, visual disturbances (I sometimes feel permanently drunk), severe hip and lower back pain which I put down to my arthritis. I do need to mention here that four years ago my sister was diagnosed with MS and my brother with ulcerative colitis. I know, there has to be some genetic pre-disposition here but what I would give to find a cure – just about anything. Since my B12 shots many of my symptoms improve, it takes four days or so after the shot and then I feel great for about a week and then some symptoms return. You have to appreciate here that I can’t help asking myself if it’s all in my head. I would be grateful for any feedback from anyone who has had a similar experience and how many shots should I keep having? I have had three shots over a period of six weeks. My GP is very good and in comparison to my specialists is far more knowledgeable and open to suggestions. After all, she was the one who tested me for Vitamin D deficiency and diagnosed me with PA. Would you believe since my first lesion over 14 years ago, I was never tested for B12 deficiency by any of the specialists?