Pernicious Anaemia Society
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Hopefully on the mend

Hi all

Loading doses completed 11/9/17 my aching has improved although not gone completely. doc said can take weeks to months for my nervous system to repair. ... my thinking/memory had also improved....although the real test will be wen I return to work (on sick due to how ill I have been) I wake up last few mornings with almost like a hungover feeling -any one else had this?? -not touched alcohol for weeks. Anyways I said I would update so here it is x

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Hi Rhi83 thanks for the "update".

It is not uncommon for some symptoms to appear to get worse before they get better as the B12 starts repairing the damage done to your nervous system and your brain starts getting multiple messages from part of the body it had "forgotten about" or lost contact with.

I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you.

A lot will depend on the severity and longevity of your B12 deficiency as to how long before there is no further improvement or recovery. Some symptoms will "disappear" quite quickly whereas others may take months or even years. There is no set timescale as we are all different.

It is also important that your Folate level is monitored as this is essential to process the B12.

There is a complex interaction between folic acid, vitamin B12 and iron. A deficiency of one may be "masked" by excess of another so the three must always be in balance.

Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body.

I hope your improvements continue, you can get back to work and I wish you well.

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