Pernicious Anaemia Society
14,653 members10,435 posts

I'm New Here

I'm 64 and have had PA for 22 years and struggle with the last 4-6 weeks of my 12 week injection. I have used B12 sublingual liquid and tablets plus Folic Acid tablets. They have porvided some relief in the past but I'm looking for help/imformation. Like many on this site I'm struggeling to get my Dr to move away from the 12 injection. Having read some of the posts I'm encouraged by the information and support. I'll keep reading and when I've got my foggy brain round things I hope to post again. Thanks Peps

1 Reply

If you have neurological symptoms you should have injections every eight weeks.

Treatment of cobalamin deficiency

Current clinical practice within the U.K is to treat cobalamin deficiency with hydroxocobalamin in the intramuscular form outlined in the British National Formulary, BNF,

Standard initial therapy for patients without neurological involvement is 1000 μg intramuscularly (i.m.) three times a week for two weeks, then every three months.

The BNF advises that for Pernicious anaemia and other macrocytic anaemias patients presenting with neurological symptoms should receive 1000 μg i.m. on alternative days until there is no further improvement, then 1 mg every 2 months.

However, the GWG recommends a pragmatic approach in patients with neurological symptoms by reviewing the need for continuation of alternative day therapy after three weeks of treatment

1 like

You may also like...