For life?: Hi guys, Just wanted an... - Pernicious Anaemi...

Pernicious Anaemia Society

32,672 members24,065 posts

For life?

Natty91 profile image
5 Replies

Hi guys,

Just wanted an opinion please. So my b12 reading was 121 and my follate levels are 9.3 ug/L. I have just finished all my injections and introduced more meat into my diet. My symptoms have improved, i have fatigue and anxiety but other than that seem to be fine.

My next blood test is in May and i have no more scheduled injectikns and will not be taking any supplements. If my levels show to be much improved would you suggest maybe that this low was a one off? What would you say is a good healthy level?

Any help will be appreciated thanks 😊

Written by
Natty91 profile image
Natty91
To view profiles and participate in discussions please or .
Read more about...
5 Replies
Secondchance profile image
Secondchance

BCSH guidelines say to continue treatment if there is a symptomatic improvement and not to retest after starting treatment. Treatment should only be stopped if a reversible cause has been identified and corrected.

Natty91 profile image
Natty91 in reply toSecondchance

But if my symptoms go and levels go up then surely theres no problem?

Secondchance profile image
Secondchance in reply toNatty91

If both these things happen, I suppose so but if there is an absorption problem then symptoms will eventually come back and levels go down. Personally, I would not risk that after my experience if no reversible cause was found. It is up to every individual though. Fatigue and anxiety are also possible symptoms for some people. Good luck with whatever you decide, but please do make sure you go back sooner if symptoms start to recur.

Gambit62 profile image
Gambit62Administrator

Although a B12 deficiency can be caused by lack of B12 in the diet this tends to happen if you are a vegan and eat no meat, dairy fish or egg.

Do you really have any justification for believing that your deficiency was down to diet?

The amount of B12 you need is very small so if you have B12 in your diet then it would unlikely that you have a dietary deficiency if you were eating meat ...

More normal for a B12 deficiency to be caused by an absorption problem - PA an autoimmune response that attacks the mechanisms that enable absorption of B12 in the ileum, is one possibility. Others include low stomach acidity, drug interactions, gastric surgery affecting the ileum, general absorption problems like Crohn's disease, h pylori infection.

The ileum is where 99% of your B12 is absorbed. B12 is stored in the liver in good quantities and then released in bile back into the ileum for reaborption as it is needed but if you have an absorption problem in the ileum this just becomes a leaky bucket.

Its unlikely that adding more meat to your diet is going to do any good because you would need to be eating 100x+ the amount of meat you were eating before.

The amount of B12 you need a day is about 2.4mcg - a 1000mcg injection is 400x that amount - and that is swimming around in your blood but it will be removed by the kidneys - generally you lose about 1/2 in the first 48 hours but the rate gets lower as you the level in your blood gets lower.

Right now your blood levels are going to be sky high. People vary in the rates at which they excrete B12 but by next May the chances are you will be back to being very deficient and very unwell, but ...

Raven321 profile image
Raven321

A good healthy level is the level that makes you feel better! Take the injections and as you feel better ease off them.. as far as I know you can't overdose on them and everyone feels better at different levels..

Peace ✌️:)

Not what you're looking for?

You may also like...

No more injections for 3 months

hello, Just wanted to get the thoughts of forum members on this... My b13 levels have gone from...
katamarang profile image

Looking for advice

Hello, I started suffering from balance problems and many other symptoms suggestive of low b12 at...
Swallow17 profile image

B12 Deficiency & Vitamin D Deficiency & Polymyalgia Rhumatica!

Hi group of fellow sufferers.... I was diagnosed with Polymyalgia Rhumatica, Vitamin D and B12...
Mariemcdo profile image

B12 & B Complex confusion

Hello I am a member of both the PA group & Thyroid UK (I have Hashimotos) 3 months ago my B12 was...
janey1234 profile image

B12 Recovery

Hello all, In November I was diagnosed with MTHFR mutation (homozygous) and very low B12 at 128....

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.