a question:-can you have negative partial gastric antibody result but still have P.A?

[autoimmunekate]

Just curious??

[wedgewood]

Yes you can. I tested positive to antibodies to the Intrinsic factor but negative to gastric parietal antibodies.

[MariLiz]

I believe so. The test can be unreliable and give a false negative result.

[fbirder]

Here's what the British Committee for Standards in Haematology say about anti-GPC antibody testing - bcshguidelines.com/document...

Gastric parietal cell antibodies (GPC antibodies) have a low specificity for the presence

of pernicious anaemia since, despite being positive in 80%

and

Anti-gastric parietal cell antibody testing for diagnosing pernicious

anaemia is not recommended (Grade 1A).