high levels vit..b12. ..any suggestions

[saramacias7]

I have high b12 .3,700..normal white/red blood count..my dr sent me to hematology..I still don't have answer what is causing it..I'm female 45...

[humanbean]

This might be helpful for both you and your doctor :

qjmed.oxfordjournals.org/co...

[clivealive Forum Support in reply to humanbean]

I was unable to open this link - all I got was a blank PDF screen humanbean .

[humanbean in reply to clivealive]

It's a pdf file. Have you got a pdf viewer installed on your device that allows you to read pdf files within your browser?

[humanbean in reply to clivealive]

Do a Google search for

"The pathophysiology of elevated vitamin B12 in clinical practice"

and see if you can open the file that way? It is a full paper, not just an abstract.

Ah! Try this link :

qjmed.oxfordjournals.org/co...

It isn't a pdf it is just a normal web page.

[clivealive Forum Support in reply to humanbean]

That worked thanks humanbean but the article was way above my understanding.

I guess 99% of folk on this forum are concerned with low levels of B12 as opposed to saramacias7 for whom I have great sympathy and hope the article will really be of help

[humanbean in reply to clivealive]

Hi Clive,

saramacias7 and I have something in common. My B12 is always high but I had lots of B12 deficiency symptoms. I supplement 5000mcg methylcobalamin every day and it has made me feel much better than I used to feel. Since supplementing my level is always reported as being

> 2000 ng/L.

[clivealive Forum Support]

Hi saramacias7 I'm not a medically qualified person but would ask are you self injecting or supplementing B12 otherwise? Do you know your folate level as this is essential to process B12.

In addition to red meat and dairy products do you have a lot of the following in your diet?

Shellfish - Whether eaten raw, steamed or grilled, different types of shellfish like clams and mussels are loaded with vitamin B12.

Caviar - Though usually only eaten as a garnish to a larger dish, fish eggs can provide more than 10 times as much vitamin B12 as chicken eggs!

Seafood - Fish, crabs, lobster and octopus are just a few of the foods that are packed with vitamin B12. They may not be everyday foods, but you should try to find creative ways to incorporate them into your diet if you're deficient in vitamin B12.

Whatever the cause, high levels of B12 are not considered dangerous per se as any excess is excreted in the urine.

Serum b12 tests are notoriously inaccurate and totally meaningless if you are supplementing.

On page 11 in the book "Could it be B12? – an epidemic of misdiagnoses” by Sally M. Pacholok R.N., B.S.N. & Jeffrey J. Stuart, D.O. under the heading "Types of tests for B12 Deficiency" talking about the Serum Vitamin B12 Test it says:-

"However, it appears that these markers demonstrate B12 deficiency primarily in patients whose serum B12 is in the "gray zone" (a serum B12 result between 200 pg/ml and 450 pg/ml). We believe that the "normal" B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebral spinal fluid (CSF) below 550 pg/ml

At this time, we believe normal serum B12 levels should be greater than 550 pg/ml. For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1,000 pg/ml."

I wish you well for the future

[saramacias7 in reply to clivealive]

that's why I really concerned..I don't take any supplements..I hardly eat meat and no fish...my folic..was normal..my dr has been doing lab work every 3 months...now it's been 1 1/2 since they discovered it..due to its have alot of fatigue....

[clivealive Forum Support in reply to saramacias7]

I do hope someone will come up with some answers for you saramacias7

humanbean 's article looked interesting but above my understanding.