I was listening to NPR this morning and heard this story:
It's about how some hospital ERs are trying to cut down on opioid use by finding alternative pain management solutions. I was mildly dismayed to hear that one hospital in New Jersey has opted to use laughing gas as a first option instead. If that becomes a widespread practice, we may all need to start wearing medical alert jewelry stating 'no nitrous oxide' on it. Laughing gas inactivates B12 and could quickly bring on all of our usual deficiency symptoms.
Most of the literature on this subject relates to long term abuse of nitrous oxide, rather than one-time administration, but, as is mentioned in the lancet article I've linked to above, there are cases where one dose does cause problems.