Pernicious Anaemia Society
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Skin cream vs patch

My doctor informed me that my PA will not allow me to absorb b12 in ANY form I take orally (pills, supplements, sublingual - even eating b12 rich foods). I was taking 1x a month cyanocobalamin injections but have never felt any relief in symptoms. Plus, getting the b12 prescription and needles is an act of congress. Now I see that methylcobalamin is readily available in topical skin creams (appx 700mcg per dose) and patches (1 patch per week, 1000mcg). Has anyone had good/bad/better experiences with either?

Thank you

2 Replies

Im a patch person, but the ones i use are much higher at 5000. They seem to work for me, no pins and needles, burning. I guess it depends on what you actually need it for symptom wise. I got headaches when i first tried them on my neck as suggested, used on arm and no problems since.


My daughter is using the yuliv nasal spray and it appears that she is absorbing b12 as her levels have gone from 345 to 866 in a few weeks. She is definitely less tired although the brain fog and concentration levels are still very poor.


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