I've recently been told I have a B12 deficiency and macrocytosis. Main symptoms are fatigue and depression. Blood tests showed B12 level of 83, so I was given 6 loading jabs which put the level up to over 2000! Unfortunately, I don't feel any better, and I've felt this way for years. I used to take multivitamins every day for many years and wonder if they could have prevented a deficiency being picked up in earlier blood tests. Any help would be appreciated, thanks.