Greetings. I'd been wondering how to get the most out of my CD/LD and was curious about which protein-rich foods - chicken or chickpeas? - interfered most with levodopa absorption.
It's 3 particular animo acids in protein that are the culprits - branched-chain amino acids (or BCAAs) named leucine, isoleucine and valine.
Learning what foods had high levels of any or all of them seemed important. What I ran across only gave more pause.
I’ve avoided eating tuna sandwiches or fish-n-chips within that hour or two of taking the CD/LD. But having a spinach salad with alfalfa sprouts and raw mushrooms, instead? That may not give the levodopa as much of a chance as you'd think.
Per 200 calories, here are the amounts of those 3 amino acids in these particular foods:
Tuna fish, canned, in water:
Leucine: 3574mg Valine: 2266mg Isoleucine: 2026mg
Leucine: 3519mg Valine: 2230mg Isoleucine: 1994mg
Leucine: 1939mg Valine: 1400mg Isoleucine: 1278mg
Alfalfa seeds sprouted:
Leucine: 2322mg Valine: 1261mg Isoleucine: 1243mg
Source: "SELF Nutrition Data: Know what you eat” a chart listing the foods w the hghest amounts of leucine, isoleucine and valine nutritiondata.self.com/food... and this chart listing the valine content only:http://nutritiondata.self.com/foods-011088000000000000000-1.html
These are the mg counts per 200 calories and granted, you'd have to eat a big pile of spinach, Popeye, to take in 200 cal. But even at half that or a quarter, that still means amino acids competing with the levodopa for absorption through the gut, aminos that before seeing this, I wouldn’t have suspected were there.
This suggests it’s not enough to follow the simplistic instructions to "avoid protein" but that I have to be vigilant and learn in what foods these particular amino acids lurk. That, or just don’t eat, period, around med time.
I’m not a dietician, nor a nutritionist. Just a PWP trying to eke out every last bit of l-dopa, so that I don’t have to increase my dosage beyond the current 25/100 3xa da. I hope someone better versed in how the body absorbs amino acids can shed some more light on all of this.