I had DBS surgery in August & chose the asleep method done at UCSF. It's been slow going as my Graves Disease came to life again after being removed with radioactive iodine 10 yrs ago. We are still fine tuning & keep hoping for solutions. I take comtan & car/levo every hour & 45 minutes. The only improvement there is that I can sleep thru' the night , but still taking all other pills. Getting frustrated as the thyroid is a mystery as is PD.