Niraparib

[Tabby13]

I have been on niraparib for two and a half years, has been fine but now developed a lot of joint and muscle aching. Does anyone else suffer with this or is it just a coincidence and not the meds? Thank you!

[Moominalong]

Good question! I’d really like to know that too. “First reoccurrence” is a new phrase to me too which I wasn’t really aware of. Nasty implications…

[Bliss31]

Hi Tabby13,

I’ve been on Niraparib for just over a year now and I get aching muscles and joints especially in the mornings when I wake up. I find after I start to move about it tends to wear off. I think I read in the very long list that it is a possible side effect.

[Tabby13 in reply to Bliss31]

Thank you Bliss31 I suspected that!

[Georgiatec]

Hi Tabby, I have taken it for 4 years, and have to say joint and bone pain, is my top symptom I suffer this. My Oncologist will give me steroids to relieve this, but only twice a year. I take Naproxen and Paracetamol.

[Tabby13 in reply to Georgiatec]

Hi Georgiatech thank you for reply, I am having to take painkillers but I have been told I will be coming off it after 3 years. What dose are you on, I am on 100mg ?

[Tulips66]

Hi Tabby , I was Niraparib for 11 mths in 2023 & didn't suffer from painful joints & muscles at the time . I started back on chemo last March till July & now I am on Avastin as maintenance, which I have been on before ,but this time my joints & muscles are so painful . When I get up in the morning I can hardly walk I am so stiff , the same thing after I have been sitting down . I enjoy walking everyday & I find it very hard when starting off but once I get moving it starts to ease . I did mention it in the hospital but they didn't prescribe me anything to ease it . I am not sure if it's the after effects of having been on the Niraparib or if it's just because of all the treatments I have been on constantly since 2019. I think maybe my body is now protesting. I started taking vitamins for my joints but they didn't really help. It might be no harm to mention it when you go to see your nurse specialist & see if she can prescribe something to help you. Good luck going forward

[Tabby13 in reply to Tulips66]

Thank you Tulips66 there seems to be alot of trial and error with meds we are put on. I shall keep going on niraparib as it seems to be working at the moment. Best wishes and I hope you stay well.

[Schnauzer19]

Hi, I’ve been on Niraparib for 9 months and have terrible stiff joints on standing from laying down, especially when I wake up in the mornings, but once I start hobbling around it goes away. I think it’s probably the parps plus chemo, they all take a toll on the body. Best wishes x

[Tabby13 in reply to Schnauzer19]

Hi yes it's the price we have to pay for hopefully staying well! I am only on a low dose. Xx