Niraparib & the Sun?

[riverside]

Hi everyone

Have been successfully on early access Niraparib for 10 months but shocked to find that when I sit in the sun I get a prickly burning sensation especially in my ankles. Has anyone else had this problem? Thanks, Marie

[cathy14_devon]

Hi ! Yes me too, mine on back of hands and face like hot pins and needles esp if there is a breeze on my skin. Factor 30 stops it, but also get it when the shower is too hot.!!

[riverside in reply to cathy14_devon]

Yes the breeze thing is interesting. Will try anti-histamines I think. Thanks for reassuring me. I will certainly mention it to the Prof when I see him next. M

[Maxjor]

Hi Riverside--here in the U.S. it says my PARP makes me "photosensitive" so to wear sunscreen outside no matter what and not to go into direct sunlight (ie. sunbathe). I love sitting on the beach so this will be difficult! oxox

[riverside in reply to Maxjor]

Oh well little ghosts we will have to be. The burning and itching on my feet at night is driving me crazy but am now taking anti-histamines to see if that works

[sandisp9]

I have the same issue on my toes. Any sun exposure makes them feel as though they are severely burned even if I use sunscreen. My doctor said it’s probably because the DNA is being damaged and this drug inhibits DNA repair.

[riverside in reply to sandisp9]

They inhibit the cancer cells from repairing themselves but that shouldn’t involve DNA. Weird - I don’t think that they know enough about how it works and what the side effects are. M

[Hidden in reply to sandisp9]

I too had this - really wierd - I expected to see massive blisters, but it just felt like it.

[riverside]

Yes exactly that. Have stayed out of the sun for a couple of days and it’s getting better.

[Superkim]

I've been on Niraparib since May. I can only be in the sun for short periods of time or I start to feel like my skin is on fire. Ears and shoulders are the worst. I now wear water shirts in the pool and keep some SPF50 in my handbag. I've also noticed that I tan (and burn) a lot easier. I'm normally very pale and right now I look like I've spent the last two months on the beach.