Hope your day is nice.Today i am having very hard time normalising because my CA 125 keeps rising and just figured now its 278..Have been on Doxil and Avastin 2 rounds.i had scheduled chemo on friday but my doctor thinks its not working and it needs to be changed. I am 43 years old had debulking in 2020 than 6 chemo rounds of taxol carbo..than 1.5 years later.carbo doxil and avastin..buy this year after Ct showing all looks good in march than in end of april Ca 125 started to rise nonstop..Please share what you did in similar situation.Your advise is greatly apreciated as we all are real people dealing with the same issue .Its much steonger to learn from our community here than read statistics in my opinion.Good lucknto all of you.God Bless You.
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See what your Oncologist suggests but Clinical Trials are always an option. My Oncologist was scratching her head with me this time last year so I asked to be referred to the Royal Marsden and I've been under their care ever since. Good luck, Kerry x
hi have you had a recent scan to confirm that the Doxil and Avastin isn’t working anymore? Don’t quote me on this but I’m sure ive heard before that the ca 125 can sometimes increase on Doxil before it starts dropping.Do you have symptoms?
I would ask about weekly taxol. I was on doxil and it did not work for me, but weekly taxol has been working for me. Ca125 went from 750 to 58 after 9 infusions.
wow.perfect.God Bless you.I bet weekly taxol ill be with 1000 side effects but if its tolerable ill go for it..i got bold in 2 weeks with low wbc..and rbc .than they infused zarzeo..kisses to you my dear
Lst look for trials 2nd talk to a good onc and/or get a 2nd opinion as there is a grest deal of resesrch and news on new combos of monoclonal antibodies with chemo or vaccine trials or immunotherapy hugs from paris
hugs from Paris..thia was great.love paris and might come back in march.Hugs backnto you from California..Vaccine for cancer would be woooooww..dusnt hear for that.immunotherapy didnt help i tried keytruda..but thanks thanks.kisses.have a great day
There is a test called a Circulating Tumor Cell test that originated in Switzerland in 2004 called the RGCC test. Some integrative oncologists utilize it in the US. There is a version of it that was FDA approved a couple of years ago. One company that does it is called CellSearch but there are a bunch more. This is a simple blood draw. If any circulating tumor cells (cells that have broken off from an existing tumor) or tumor DNA is found then they are able to tell where in the body the tumor originated as well as any genetic mutations. This could help with early recurrence detection as well as matching with treatments based on genetic mutations. This test is essentially a liquid biopsy and is able to detect tumors before they are even large enough to appear on a scan.
Most oncologists don’t use it for “clinical application” yet because its supposedly “new” technology even though its been around since 2004. MD Anderson just adopted it under standard of care at their practice 2 years ago. Your oncologist could order the test even if they don’t typically do so. This might give you a better idea of your situation instead of waiting and watching on scans. If any circulating tumor cells are found the original RGCC test can even test 53 types of chemo on your cells to find out if they are chemo sensitive.
There is a Bill in the Senate that was introduced in 2021 called the Medicare Multi-Cancer Early
Detection Screening Coverage Act that is pushing to have this test covered by medicare as a screening and early detection tool for the general public as well as a way for cancer patients to be monitored after treatment. I just spoke to my oncologist about it and after some insisting he agreed to order the test. This might help you have some peace of mind if you have a more accurate screening tool utilized like this blood test and a better assessment of your condition.
Avastin kept my CA 125 in check for quite a while. Lately it is creeping up. My Onco is putting me on CYTOXAN 50 mg per day. I can keep you posted how it is affecting my CA 125. All the best to you as we fight this battle together.❤️🙏
THANK YOU so much Leniko.Good luck to you and Ill ask my doctor about Cytoxan next week.Please let me know once you have Ca 125 reading.Good luck and yes we arw here to suppprt each other.Hugs from California
I am on cisplatin and Gemzar seems to be doing the trick. Week 1 Cisplatinum and Gemzar …week 2 just Gemzar…. Week 3 break. I have had 2 treatments my CA 125 cut in half it is working for me but everything is different for everybody. Strength and positive attitude be with you this disease sure can manipulate itself. Your Onc has other things in their back pockets I am sure of it This website gives us so much information it is wonderful the support we get! Good luck keep fighting Teal Ladies Stay Strong!
Thank you dear Summergold.Ill ask for your treatment regimen also..Now i am waiting for pet scan approval to see whats going there that Ca 125 keeps rising.but i feel good.Yes we all support each other in here with the best real strong woman and their journey...God Bless You😘
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Please, Any good news Calyx/doxil
Cabo / doxil / avastin 
High CA125, chemo/avastin not working 
How long does it take Avastin to start working? What if it isn't working?
Avastin no longer working, next steps?
