Experience on Carbo/ Gemzar

[win_56]

Hi everyone, I'm started chemo combination of Csrboplayin and Gemzar tomorrow. Has anyone done thus combo and any advice ? Thanks

[Caleda4]

Hello Win,Yes I did carbo/gemzar in 2020,and for me it was ok and relatively easy. I did feel very tired on 3rd to 4th day but after that absolutely fine.

My regime was carbo/gemzar which took a morning generally on week one,the on week two gemzar only which took less than an hour,then 2weeks off and the same again. I had six cycles.

I hope everything goes well for you. Take care.x

[win_56 in reply to Caleda4]

Thanks Caleda yes it seems exactly the same cycle I'm going on. Thanks for your reply.Hope you're doing ok? X

[megb246]

Hi June im sorry you back on chemo i thought the parbs were working for you . If it makes you feel better nirapairb has stopped working for me so am looking at an op then more chemo . At least we have had nearly a year ! Did you ever get little dog ? Take care Meg xx

[win_56 in reply to megb246]

Hi Meg long time no hear but to be honest I wasn't coping very well on the forum having lost so many of our teal warriors and had a long break from it and had sone counselling from Macmillan as it affected be greatly. I was on the Rubraca for the 3 lymph nodes after chemo had shrunk them but the lymph nodes Infront of my lumber started kicking off again after 13 months so stopped working. My oncologist said back to chemo. The year befire ingot second opinion from Royal Marsden as my surgeon would not take them out as the one was the aorta lymph node which was close to the renal artery and the other two were the same do deemed inoperable. The Marsden said the same too dangerous to take out. In October when I found out they were kicking off again I got a second opinion from Orif Chrustina Fotopolou at the Queen's Charlotte In Hammersmith and she agreed to attempt to take them out. She and her Team successfully removed them . It was not an easy operation and it took about 6 hrs just to get these nodes out as a lot of scar tissue had to be removed from orev debulking and she said a lot of blood vessels wrapped around them and they grew into one large cluster. Im now back to my team in Birmingham and having 6 rounds of chemo to mop up as so to speak. I'm not on any parb now as had progression Well that's my story. I will message you.xxx

[megb246 in reply to win_56]

Hi June ... its all a fight to get the help we need bit well done for keeping at it . I always think operations to remove cancer is best chance . I am on fourth reoccurence now as niraparib hasnt worked forme and also have heart problem from all chemo! Im awaiti g outcome of mdt meeting as my cardiologist worried about chemo so assuming it will be course of radiotherapy after operation . I too had time out from site as really good for imformation but can be deppressing at same time . Albert my dog has been my lifeline as sheilding for so long freinds drifted off you must get one !! I have moved to the countryside in december which is so peaceful compared to the town but only have log burner for heating and the cold ness takes bit of getting used too. Hope you new chemo regine isnt too awful June sending hugs meg xxx

[win_56 in reply to megb246]

Hi Meg so good to hear from you..Its a real roller coaster ride thus cancer it sucjs. One minute you think you're winning at thenntge butch tears its ugly head again, but we have to keep fighting! When I spoke to my oncologist about the second opinion with Prof C she said that the Royal Marsden was thinking about trialling radiotherapy for lymph node involvement. I too have as having heart palpitations when on Rubraca terrible.I really hope after your operation you get the radiotherapy.. So you moved to the peaceful country side sounds idyluc. We got a multi burner log/ coal and use it every might. It really heats the whole house and the living room radiators just ticking over. Live the burner Yes I keep saying I want a fog after finishing these cycles of chemo I must stop talking and get one As you say I think they keep you going and take your mind of this bloody disease. I'm trying to just get on with my life and make each day count, by going for walks, pub lunches, garden centres just days out helps take mind off things..I hope your op goes well and tlyou get a well deserved break Meg. Keep us posted on the MTD meeting decision .Hugs to you too, take care thinking of you. June.xxxx

[JustKBO]

Sorry can’t advise but wishing you good luck with the new regime. X

[win_56 in reply to JustKBO]

Thank you x

[Lizzieanne]

Thinking of you today June. Good to see your back Liz x

[win_56 in reply to Lizzieanne]

Thanks Lizzie. Xx

[delia2]

I haven’t had that combo yet but sending hugs.

[win_56 in reply to delia2]

Thanks Delia. xx

[Tulips66]

Hi Win, I was on the Carbo/Gemcitabine regime from March 2021 for first recurrence. I started off with the two chemo's on week 1 & then Gem only, 2 weeks later but unfortunately this regime played havoc with my white blood cells & I ended up having to have a Neulasta injection after chemo. Even with the injections the white blood cells weren't recovering in time for my next chemo session so I ended up just on the carbo/Gem every 3 weeks instead until Sept 2020. I have been having the Gem on its own every 3 weeks since then. I was in today getting the results of a recent Ct scan & the news is very good, remaining node has decreased further since my last scan & no evidence of disease anywhere else so its working. I am continuing on the Gem only for another few months but once its keeping the cancer away I don't mind. I know we all react to different types of chemo different ways & hopefully it won't effect your blood cells at all, but even if it does they will sort it out for you. Other than the bloods this regime is definitely easier to tolerate & doesn't effect my life too much. I wish you all the best with it & 🤞it brings you the same good results. Xx

[win_56 in reply to Tulips66]

Hi Tulip thanks for your input I really appreciate it. My oncologist said that it it very hard on the bloods and all previous chemos I've had to have blood transfusions but as you say just git to see what happens. That's brilliant news about the node shrinking and that this combo is working for you. Its always an anxious time waiting for scan results. wishing you all the very best going forward.xx

[greeneverything in reply to Tulips66]

I'm just about to start this regime. Good to hear going well.

[Tulips66 in reply to greeneverything]

Hope it goes well for you too & you will get the good results that I have got. Keep in touch and let me know how you are doing X

[greeneverything in reply to Tulips66]

Thanks. I'm also stage 3c/4 high grade serious. Diagnosed in Feb 2020.

[win_56]

Thank you. I will keep on touch.x