Chemotherapy for ovarian cancer

[Aliollie]

Hi my mums Niraparib has stopped working and is waiting for more chemo, am really worried as they said she couldn’t go on another PARP inhibitor as a maintenance drug does anyone have any help please.

Love to all Ali x

[Lyndy]

Hello, sorry to hear that niraparib stopped working for your Mum..it seems that it doesn’t work for everyone so it’s good news that her oncologist has a plan. I know chemo isn’t what we look forward to but it can be very effective. Wishing her and you all the best xx

[Ruebacelle]

Taxol works well

[Esmerelda101]

Hi Ali, My parp stopped working and I’m now back on chemo. Apparently they are not licensed to recommence Parps after an initial treatment but my oncologist is going to look at trials post chemo. May be an option for your mum? All the best with the chemo xx

[Aliollie]

Thank you for your replies keep well x could you please let me know when your oncologist finds a trial for you many thanks

[Realistic]

Your Dear Mums got a plan and with you to help Her l'm sure she will be fine sending love & hugs SheilaFxxx

[Aliollie]

Thank you I hope so x

[Gemimablackvelvet]

Hi Ali, my parp, Rucaparib didn’t work so started with Taxol. That worked for a while then stopped so back on Carboplatin. I have stage 1V with liver metastasis. Chemo does work to a high degree in most cases so your mum has every chance of a good result. Love Angela xx

[Aliollie]

Let’s hope so, this site is a blessing to give people a bit of hope, you feel really lost with what’s going on thank you. How are you doing getting on ? Sending you love and best wishes xx

[Pianoplayer731021]

Hi, just wondering how long your mom was on niraparib. I’m on that since July of 2020. They did have to lower my dose from 300 to 100. I also have to take small breaks from it, because of blood counts that are too high or low. Hope that your mom will do well with whatever they put her on. I live in the US, Donna

[Nicky100 in reply to Pianoplayer731021]

Hi Donna

I’ve been on it nearly 4 years. It’s working.

[Pianoplayer731021 in reply to Nicky100]

Hi Nicky, my dose started at 200 mgs., not 300. I was wondering what stage were you at and your age. I am 74, will be 75 in November. I was stage 4 after my surgery. It sure has been a journey. Happy that you have been on it for almost 4 years. That’s wonderful! I have neuropathy in my feet from chemo and niraparib. I also am BRCA negative, so I hope this drug will keep working ok. The BRCA positive works with this drug better, at least that’s what my dr. was saying. Good to hear from you, take care; Donna xx

[Nicky100 in reply to Pianoplayer731021]

Hi Donna,

I’m now 48 and was stage 4 in 2017. Niraparib has been brilliant for me but 200mg was too tough in my body. I cope on 100mg. Much love

Xx

[Aliollie]

Hi Donna they worked for about four months, she is just about to start carboplatin, it seems they are working for you which is great xxx

[Pianoplayer731021 in reply to Aliollie]

Thankyou Aliollie. I hope your mom’s treatment will go well with her. Hugs! Donna

[Anamcara63]

I was on niraparib and my ascities returned and they said the same to me now im bck on niraparib as i got ascities drained and if it dont work again then its chemo weekly with avastin. so theres a lot can change. my prognosis is not good but chemo worked first time so im hoping it gives me more time. i hope this helps and sending good wishes to you both.

[Aliollie in reply to Anamcara63]

Thanks for this, somebody recommended the care oncology london we are looking into that also I have just started reading how to starve cancer - Jane McLelland it may help you. I don’t know where you are in the country but dr Krell is very good Harley Street london. I hope the Niraparib is working for you love Ali xx