Just a bit of news. I'm on carboplatin only for 3rd line and on my second IV dose I had a reaction and only received half the treatment. They didn't think I recovered enough to carry on. I have extra steroids to take next time. This happened once during first line but not 2nd line when I was on gem/carbon/avastin. My CA 125 has already started to fall a bit so in the back of my mind I'm worried that I won't be able to continue treatment, though I carried on without a further reaction the first time round.