Hi all, I am having 4 th line weekly Taxol and although the Dr seems to think its working as CA 125 reducing I am having a hard time with weeekly ascitic drainage. They are now going to refer me for a permanent drain. Also having a lot of trouble with lymphodema in my legs. To-day I feel really down and feel that I am coming to the end of the road. I just wondered if any of you have experience of the permanent drain etc and can give me any positives. Thanks and hope everyone is keeping as well as possible.