I toddled off to the gp today as had a bite which was slow to go away and casually mentioned that I had piles etc so before I knew it I have been referrred to a surgeon for colonscopy. I drove all the way home across the city freaking out. Of course he mentioned the article so he cant be blamed for not acting in the best interest of his patient. Ironic isnt it? I am just wondering if any of you would like to share if they had or have discomfort in that area while on Avastin? I do realise it is not a dinner table subject haha. I got suppositories in the meantime but I have to keep the hospital appointment even if it clears up. I did notice it worsened after the last Avastin. My last ct scan was good enough and lymph nodes are down but he said it was a red flag complaint so had to be followed up. Oh the bite could be a spider bite or a little cyst which isnt a major thing.