I'm scheduled for a hysterectomy 22nd April and have been advised by my rheumatology nurse that there's no need to stop mtx prior to surgery or after. I'm feeling a bit nervous about this as I thought it lowered our immune system? He did say that if my dose was due the same day it might be best not to take it. Mine is due on the Sunday and the op is on the Monday so I'm thinking of skipping that one. Anyway he said there is no evidence to support the need to stop. I was just wondering what advice you lovely lot have been given prior to surgery? Obviously my decision will be based on medical advice.