I'm experiencing more and more side effects of the mtx injections (tolerated 20mg weekly for about 5 years now) but have recently noticed that I'm suffering increased bouts of nausea (for days on end so much so that I can't eat, despite anti-sickness tablets and folic acid) and I have begun to get site reactions from injections, large red blisters that itch and can get sore and infected.
I'm also aware that I'm flaring more often, in new places too and am living on pain killers just to get me through the day/night. I feel that I'd like to stop the mtx and try something new. There was the hope that I could take something along side the mtx (hydroxychloroquine/sulphasalazine) so I could reduce the dose but I really feel that I'm ready for a complete change as it would be better for me both physically and psychologically. I couldn't take the hydroxychloroquine as it affected my eyes and so it looks like sulphasalazine might be my next option...but how effective is it on it's own?
I'm just a bit fed up of feeling so lousy, I haven't felt this down about my RA for ages. I had a really good summer and I know that these are the worst months for me so, whilst waiting for an appointment with my consultant, I thought I'd ask if any of you lovely, helpful people had any good, honest advice? What might my next option be? Should I ask to try a biological? Is that even an option in Cumbria...anyone know?