Has anyone had to wait ages for it to kick in?! I started on 10mg a day about 11 days ago, and feel as though I've really gone backwards! Stopped leflunomide at the same time, and am currently just on pred and hydroxy, but feeling joint pains returning in many joints! And don't even have that feeling of loads of energy / insomnia etc that many seem to get from pred! I've been more exhausted on it than I have been for a while!