Just back from the hospital and now been told instead of sero neg ra I now have pa. So no more Humira for me. Now on ciclosporin twice a day. Dmard number 5. I dont know why the change as nothing new has happened apart from more and more joints are getting painful but the only skin problem is a red patch from where I had a steroid injection 3 weeks ago. My bloods as normal are fine ESR 11 and CRP 2 anyway I guess I will have to wait and see if it helps with the pain in my knees, hips and fingers, I would really love a good night sleep.I putting that on my christmas list. Thanks, its helps to have somebody to discuss these things with.